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Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.
Pitcher MR, Ward CS, Arvide EM, Chapleau CA, Pozzo-Miller L, Hoeflich A, Sivaramakrishnan M, Saenger S, Metzger F, Neul JL. Pitcher MR, et al. Among authors: sivaramakrishnan m. Hum Mol Genet. 2013 Jul 1;22(13):2626-33. doi: 10.1093/hmg/ddt111. Epub 2013 Mar 5. Hum Mol Genet. 2013. PMID: 23462290 Free PMC article.
PEGylation of lysine residues reduces the pro-migratory activity of IGF-I.
Sivaramakrishnan M, Kashyap AS, Amrein B, Saenger S, Meier S, Staudenmaier C, Upton Z, Metzger F. Sivaramakrishnan M, et al. Biochim Biophys Acta. 2013 Oct;1830(10):4734-42. doi: 10.1016/j.bbagen.2013.06.012. Epub 2013 Jun 23. Biochim Biophys Acta. 2013. PMID: 23800578 Free article.
Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.
Naryshkin NA, Weetall M, Dakka A, Narasimhan J, Zhao X, Feng Z, Ling KK, Karp GM, Qi H, Woll MG, Chen G, Zhang N, Gabbeta V, Vazirani P, Bhattacharyya A, Furia B, Risher N, Sheedy J, Kong R, Ma J, Turpoff A, Lee CS, Zhang X, Moon YC, Trifillis P, Welch EM, Colacino JM, Babiak J, Almstead NG, Peltz SW, Eng LA, Chen KS, Mull JL, Lynes MS, Rubin LL, Fontoura P, Santarelli L, Haehnke D, McCarthy KD, Schmucki R, Ebeling M, Sivaramakrishnan M, Ko CP, Paushkin SV, Ratni H, Gerlach I, Ghosh A, Metzger F. Naryshkin NA, et al. Among authors: sivaramakrishnan m. Science. 2014 Aug 8;345(6197):688-93. doi: 10.1126/science.1250127. Science. 2014. PMID: 25104390
Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers.
Sivaramakrishnan M, McCarthy KD, Campagne S, Huber S, Meier S, Augustin A, Heckel T, Meistermann H, Hug MN, Birrer P, Moursy A, Khawaja S, Schmucki R, Berntenis N, Giroud N, Golling S, Tzouros M, Banfai B, Duran-Pacheco G, Lamerz J, Hsiu Liu Y, Luebbers T, Ratni H, Ebeling M, Cléry A, Paushkin S, Krainer AR, Allain FH, Metzger F. Sivaramakrishnan M, et al. Nat Commun. 2017 Nov 14;8(1):1476. doi: 10.1038/s41467-017-01559-4. Nat Commun. 2017. PMID: 29133793 Free PMC article.
Vitronectin--master controller or micromanager?
Leavesley DI, Kashyap AS, Croll T, Sivaramakrishnan M, Shokoohmand A, Hollier BG, Upton Z. Leavesley DI, et al. Among authors: sivaramakrishnan m. IUBMB Life. 2013 Oct;65(10):807-18. doi: 10.1002/iub.1203. Epub 2013 Sep 13. IUBMB Life. 2013. PMID: 24030926 Free article. Review.
Transglutaminases and receptor tyrosine kinases.
Sivaramakrishnan M, Shooter GK, Upton Z, Croll TI. Sivaramakrishnan M, et al. Amino Acids. 2013 Jan;44(1):19-24. doi: 10.1007/s00726-011-1113-x. Epub 2011 Oct 11. Amino Acids. 2013. PMID: 21986960 Review.
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