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Workshop on the validation and regulatory acceptance of innovative 3R approaches in regulatory toxicology - Evolution versus revolution.
Burgdorf T, Piersma AH, Landsiedel R, Clewell R, Kleinstreuer N, Oelgeschläger M, Desprez B, Kienhuis A, Bos P, de Vries R, de Wit L, Seidle T, Scheel J, Schönfelder G, van Benthem J, Vinggaard AM, Eskes C, Ezendam J. Burgdorf T, et al. Among authors: clewell r. Toxicol In Vitro. 2019 Sep;59:1-11. doi: 10.1016/j.tiv.2019.03.039. Epub 2019 Apr 1. Toxicol In Vitro. 2019. PMID: 30946968
Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays.
McMullen PD, Andersen ME, Cholewa B, Clewell HJ 3rd, Dunnick KM, Hartman JK, Mansouri K, Minto MS, Nicolas CI, Phillips MB, Slattery S, Yoon M, Clewell RA. McMullen PD, et al. Toxicol In Vitro. 2018 Apr;48:310-317. doi: 10.1016/j.tiv.2018.01.027. Epub 2018 Jan 31. Toxicol In Vitro. 2018. PMID: 29391263 Free article. Review.
Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalates.
Clewell RA, Leonard JA, Nicolas CI, Campbell JL, Yoon M, Efremenko AY, McMullen PD, Andersen ME, Clewell HJ 3rd, Phillips KA, Tan YM. Clewell RA, et al. Toxicol In Vitro. 2020 Aug;66:104855. doi: 10.1016/j.tiv.2020.104855. Epub 2020 Apr 8. Toxicol In Vitro. 2020. PMID: 32278033 Free PMC article.
Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment.
Adeleye Y, Andersen M, Clewell R, Davies M, Dent M, Edwards S, Fowler P, Malcomber S, Nicol B, Scott A, Scott S, Sun B, Westmoreland C, White A, Zhang Q, Carmichael PL. Adeleye Y, et al. Among authors: clewell r. Toxicology. 2015 Jun 5;332:102-11. doi: 10.1016/j.tox.2014.02.007. Epub 2014 Feb 25. Toxicology. 2015. PMID: 24582757 Free article.
56 results