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Disposition and metabolism of GSK2251052 in humans: a novel boron-containing antibiotic.
Bowers GD, Tenero D, Patel P, Huynh P, Sigafoos J, O'Mara K, Young GC, Dumont E, Cunningham E, Kurtinecz M, Stump P, Conde JJ, Chism JP, Reese MJ, Yueh YL, Tomayko JF. Bowers GD, et al. Among authors: chism jp. Drug Metab Dispos. 2013 May;41(5):1070-81. doi: 10.1124/dmd.112.050153. Epub 2013 Feb 25. Drug Metab Dispos. 2013. PMID: 23439661
An unexpected synergist role of P-glycoprotein and breast cancer resistance protein on the central nervous system penetration of the tyrosine kinase inhibitor lapatinib (N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine; GW572016).
Polli JW, Olson KL, Chism JP, John-Williams LS, Yeager RL, Woodard SM, Otto V, Castellino S, Demby VE. Polli JW, et al. Among authors: chism jp. Drug Metab Dispos. 2009 Feb;37(2):439-42. doi: 10.1124/dmd.108.024646. Epub 2008 Dec 4. Drug Metab Dispos. 2009. PMID: 19056914
Toxicity and toxicokinetics of metformin in rats.
Quaile MP, Melich DH, Jordan HL, Nold JB, Chism JP, Polli JW, Smith GA, Rhodes MC. Quaile MP, et al. Among authors: chism jp. Toxicol Appl Pharmacol. 2010 Mar 15;243(3):340-7. doi: 10.1016/j.taap.2009.11.026. Epub 2010 Jan 13. Toxicol Appl Pharmacol. 2010. PMID: 20004680
Toxicokinetics and toxicity of atorvastatin in dogs.
Herron CE, Brueckner CC, Chism JP, Kemp DC, Prescott JS, Smith GA, Melich DH, Oleas N, Polli JW. Herron CE, et al. Among authors: chism jp. Toxicol Appl Pharmacol. 2015 Nov 15;289(1):117-23. doi: 10.1016/j.taap.2015.09.008. Epub 2015 Sep 16. Toxicol Appl Pharmacol. 2015. PMID: 26386191
18 results