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Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.
Girousse A, Tavernier G, Valle C, Moro C, Mejhert N, Dinel AL, Houssier M, Roussel B, Besse-Patin A, Combes M, Mir L, Monbrun L, Bézaire V, Prunet-Marcassus B, Waget A, Vila I, Caspar-Bauguil S, Louche K, Marques MA, Mairal A, Renoud ML, Galitzky J, Holm C, Mouisel E, Thalamas C, Viguerie N, Sulpice T, Burcelin R, Arner P, Langin D. Girousse A, et al. Among authors: waget a. PLoS Biol. 2013;11(2):e1001485. doi: 10.1371/journal.pbio.1001485. Epub 2013 Feb 19. PLoS Biol. 2013. PMID: 23431266 Free PMC article. Clinical Trial.
Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain.
Knauf C, Rieusset J, Foretz M, Cani PD, Uldry M, Hosokawa M, Martinez E, Bringart M, Waget A, Kersten S, Desvergne B, Gremlich S, Wahli W, Seydoux J, Delzenne NM, Thorens B, Burcelin R. Knauf C, et al. Among authors: waget a. Endocrinology. 2006 Sep;147(9):4067-78. doi: 10.1210/en.2005-1536. Epub 2006 Jun 15. Endocrinology. 2006. PMID: 16777972
Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment.
Amar J, Chabo C, Waget A, Klopp P, Vachoux C, Bermúdez-Humarán LG, Smirnova N, Bergé M, Sulpice T, Lahtinen S, Ouwehand A, Langella P, Rautonen N, Sansonetti PJ, Burcelin R. Amar J, et al. Among authors: waget a. EMBO Mol Med. 2011 Sep;3(9):559-72. doi: 10.1002/emmm.201100159. Epub 2011 Aug 3. EMBO Mol Med. 2011. PMID: 21735552 Free PMC article.
Liraglutide targets the gut microbiota and the intestinal immune system to regulate insulin secretion.
Charpentier J, Briand F, Lelouvier B, Servant F, Azalbert V, Puel A, Christensen JE, Waget A, Branchereau M, Garret C, Lluch J, Heymes C, Brousseau E, Burcelin R, Guzylack L, Sulpice T, Grasset E. Charpentier J, et al. Among authors: waget a. Acta Diabetol. 2021 Jul;58(7):881-897. doi: 10.1007/s00592-020-01657-8. Epub 2021 Mar 15. Acta Diabetol. 2021. PMID: 33723651
CX3CR1 regulates gut microbiota and metabolism. A risk factor of type 2 diabetes.
Pomié C, Servant F, Garidou L, Azalbert V, Waget A, Klopp P, Garret C, Charpentier J, Briand F, Sulpice T, Lelouvier B, Douin-Echinard V, Burcelin R. Pomié C, et al. Among authors: waget a. Acta Diabetol. 2021 Aug;58(8):1035-1049. doi: 10.1007/s00592-021-01682-1. Epub 2021 Mar 22. Acta Diabetol. 2021. PMID: 33754166
A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction.
Moreno-Navarrete JM, Escoté X, Ortega F, Serino M, Campbell M, Michalski MC, Laville M, Xifra G, Luche E, Domingo P, Sabater M, Pardo G, Waget A, Salvador J, Giralt M, Rodriguez-Hermosa JI, Camps M, Kolditz CI, Viguerie N, Galitzky J, Decaunes P, Ricart W, Frühbeck G, Villarroya F, Mingrone G, Langin D, Zorzano A, Vidal H, Vendrell J, Burcelin R, Vidal-Puig A, Fernández-Real JM. Moreno-Navarrete JM, et al. Among authors: waget a. Diabetologia. 2013 Nov;56(11):2524-37. doi: 10.1007/s00125-013-3015-9. Epub 2013 Aug 21. Diabetologia. 2013. PMID: 23963324
Metabolic endotoxemia initiates obesity and insulin resistance.
Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, Bastelica D, Neyrinck AM, Fava F, Tuohy KM, Chabo C, Waget A, Delmée E, Cousin B, Sulpice T, Chamontin B, Ferrières J, Tanti JF, Gibson GR, Casteilla L, Delzenne NM, Alessi MC, Burcelin R. Cani PD, et al. Among authors: waget a. Diabetes. 2007 Jul;56(7):1761-72. doi: 10.2337/db06-1491. Epub 2007 Apr 24. Diabetes. 2007. PMID: 17456850
38 results