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Linking phenotype to kinase: identification of a novel benzoxaborole hinge-binding motif for kinase inhibition and development of high-potency rho kinase inhibitors.
Akama T, Dong C, Virtucio C, Sullivan D, Zhou Y, Zhang YK, Rock F, Freund Y, Liu L, Bu W, Wu A, Fan XQ, Jarnagin K. Akama T, et al. Among authors: virtucio c. J Pharmacol Exp Ther. 2013 Dec;347(3):615-25. doi: 10.1124/jpet.113.207662. Epub 2013 Sep 18. J Pharmacol Exp Ther. 2013. PMID: 24049062
Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes.
Dong C, Virtucio C, Zemska O, Baltazar G, Zhou Y, Baia D, Jones-Iatauro S, Sexton H, Martin S, Dee J, Mak Y, Meewan M, Rock F, Akama T, Jarnagin K. Dong C, et al. Among authors: virtucio c. J Pharmacol Exp Ther. 2016 Sep;358(3):413-22. doi: 10.1124/jpet.116.232819. Epub 2016 Jun 27. J Pharmacol Exp Ther. 2016. PMID: 27353073