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Combining functional and structural genomics to sample the essential Burkholderia structome.
Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D 3rd, Staker BL, Phan I, Gillespie A, Choi R, Nakazawa-Hewitt S, Nguyen MT, Napuli A, Barrett L, Buchko GW, Stacy R, Myler PJ, Stewart LJ, Manoil C, Van Voorhis WC. Baugh L, et al. Among authors: dranow dm. PLoS One. 2013;8(1):e53851. doi: 10.1371/journal.pone.0053851. Epub 2013 Jan 31. PLoS One. 2013. PMID: 23382856 Free PMC article.
Increasing the structural coverage of tuberculosis drug targets.
Baugh L, Phan I, Begley DW, Clifton MC, Armour B, Dranow DM, Taylor BM, Muruthi MM, Abendroth J, Fairman JW, Fox D 3rd, Dieterich SH, Staker BL, Gardberg AS, Choi R, Hewitt SN, Napuli AJ, Myers J, Barrett LK, Zhang Y, Ferrell M, Mundt E, Thompkins K, Tran N, Lyons-Abbott S, Abramov A, Sekar A, Serbzhinskiy D, Lorimer D, Buchko GW, Stacy R, Stewart LJ, Edwards TE, Van Voorhis WC, Myler PJ. Baugh L, et al. Among authors: dranow dm. Tuberculosis (Edinb). 2015 Mar;95(2):142-8. doi: 10.1016/j.tube.2014.12.003. Epub 2014 Dec 19. Tuberculosis (Edinb). 2015. PMID: 25613812 Free PMC article.
Crystal structure of betaine aldehyde dehydrogenase from Burkholderia pseudomallei.
Beard DK, Subramanian S, Abendroth J, Dranow DM, Edwards TE, Myler PJ, Asojo OA. Beard DK, et al. Among authors: dranow dm. Acta Crystallogr F Struct Biol Commun. 2022 Feb 1;78(Pt 2):45-51. doi: 10.1107/S2053230X21013455. Epub 2022 Jan 27. Acta Crystallogr F Struct Biol Commun. 2022. PMID: 35102892 Free PMC article.
Toward a structome of Acinetobacter baumannii drug targets.
Tillery LM, Barrett KF, Dranow DM, Craig J, Shek R, Chun I, Barrett LK, Phan IQ, Subramanian S, Abendroth J, Lorimer DD, Edwards TE, Van Voorhis WC. Tillery LM, et al. Among authors: dranow dm. Protein Sci. 2020 Mar;29(3):789-802. doi: 10.1002/pro.3826. Epub 2020 Jan 20. Protein Sci. 2020. PMID: 31930600 Free PMC article.
Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.
Ojo KK, Ranade RM, Zhang Z, Dranow DM, Myers JB, Choi R, Nakazawa Hewitt S, Edwards TE, Davies DR, Lorimer D, Boyle SM, Barrett LK, Buckner FS, Fan E, Van Voorhis WC. Ojo KK, et al. Among authors: dranow dm. PLoS One. 2016 Aug 8;11(8):e0160350. doi: 10.1371/journal.pone.0160350. eCollection 2016. PLoS One. 2016. PMID: 27500735 Free PMC article.
Crystal structure of chorismate mutase from Burkholderia thailandensis.
Asojo OA, Dranow DM, Serbzhinskiy D, Subramanian S, Staker B, Edwards TE, Myler PJ. Asojo OA, et al. Among authors: dranow dm. Acta Crystallogr F Struct Biol Commun. 2018 May 1;74(Pt 5):294-299. doi: 10.1107/S2053230X1800506X. Epub 2018 Apr 16. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29717997 Free PMC article.
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.
Tillery L, Barrett K, Goldstein J, Lassner JW, Osterhout B, Tran NL, Xu L, Young RM, Craig J, Chun I, Dranow DM, Abendroth J, Delker SL, Davies DR, Mayclin SJ, Calhoun B, Bolejack MJ, Staker B, Subramanian S, Phan I, Lorimer DD, Myler PJ, Edwards TE, Kyle DE, Rice CA, Morris JC, Leahy JW, Manetsch R, Barrett LK, Smith CL, Van Voorhis WC. Tillery L, et al. Among authors: dranow dm. PLoS One. 2021 Mar 24;16(3):e0241738. doi: 10.1371/journal.pone.0241738. eCollection 2021. PLoS One. 2021. PMID: 33760815 Free PMC article.
A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Clifton MC, Dranow DM, Leed A, Fulroth B, Fairman JW, Abendroth J, Atkins KA, Wallace E, Fan D, Xu G, Ni ZJ, Daniels D, Van Drie J, Wei G, Burgin AB, Golub TR, Hubbard BK, Serrano-Wu MH. Clifton MC, et al. Among authors: dranow dm. PLoS One. 2015 Apr 24;10(4):e0125010. doi: 10.1371/journal.pone.0125010. eCollection 2015. PLoS One. 2015. PMID: 25909780 Free PMC article.
33 results