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Recent developments of DNA poisons--human DNA topoisomerase IIα inhibitors--as anticancer agents.
Curr Pharm Des. 2013;19(13):2474-88. doi: 10.2174/1381612811319130016.
Curr Pharm Des. 2013.
PMID: 23363399
Review.
Monocyclic 4-amino-6-(phenylamino)-1,3,5-triazines as inhibitors of human DNA topoisomerase IIα.
Pogorelčnik B, Brvar M, Zajc I, Filipič M, Solmajer T, Perdih A.
Pogorelčnik B, et al.
Bioorg Med Chem Lett. 2014 Dec 15;24(24):5762-5768. doi: 10.1016/j.bmcl.2014.10.042. Epub 2014 Oct 22.
Bioorg Med Chem Lett. 2014.
PMID: 25453816
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Discovery of mono- and disubstituted 1H-pyrazolo[3,4]pyrimidines and 9H-purines as catalytic inhibitors of human DNA topoisomerase IIα.
Pogorelčnik B, Brvar M, Žegura B, Filipič M, Solmajer T, Perdih A.
Pogorelčnik B, et al.
ChemMedChem. 2015 Feb;10(2):345-59. doi: 10.1002/cmdc.201402459. Epub 2014 Dec 17.
ChemMedChem. 2015.
PMID: 25522133
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4,6-Substituted-1,3,5-triazin-2(1H)-ones as monocyclic catalytic inhibitors of human DNA topoisomerase IIα targeting the ATP binding site.
Pogorelčnik B, Janežič M, Sosič I, Gobec S, Solmajer T, Perdih A.
Pogorelčnik B, et al.
Bioorg Med Chem. 2015 Aug 1;23(15):4218-4229. doi: 10.1016/j.bmc.2015.06.049. Epub 2015 Jul 2.
Bioorg Med Chem. 2015.
PMID: 26183545
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Recent advances in the development of catalytic inhibitors of human DNA topoisomerase IIα as novel anticancer agents.
Pogorelčnik B, Perdih A, Solmajer T.
Pogorelčnik B, et al.
Curr Med Chem. 2013;20(5):694-709. doi: 10.2174/092986713804999402.
Curr Med Chem. 2013.
PMID: 23210851
Review.
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