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Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells.
Gandhi N, Wild AT, Chettiar ST, Aziz K, Kato Y, Gajula RP, Williams RD, Cades JA, Annadanam A, Song D, Zhang Y, Hales RK, Herman JM, Armour E, DeWeese TL, Schaeffer EM, Tran PT. Gandhi N, et al. Among authors: cades ja. Cancer Biol Ther. 2013 Apr;14(4):347-56. doi: 10.4161/cbt.23626. Epub 2013 Jan 28. Cancer Biol Ther. 2013. PMID: 23358469 Free PMC article.
The twist box domain is required for Twist1-induced prostate cancer metastasis.
Gajula RP, Chettiar ST, Williams RD, Thiyagarajan S, Kato Y, Aziz K, Wang R, Gandhi N, Wild AT, Vesuna F, Ma J, Salih T, Cades J, Fertig E, Biswal S, Burns TF, Chung CH, Rudin CM, Herman JM, Hales RK, Raman V, An SS, Tran PT. Gajula RP, et al. Mol Cancer Res. 2013 Nov;11(11):1387-400. doi: 10.1158/1541-7786.MCR-13-0218-T. Epub 2013 Aug 27. Mol Cancer Res. 2013. PMID: 23982216 Free PMC article.
Concurrent versus sequential sorafenib therapy in combination with radiation for hepatocellular carcinoma.
Wild AT, Gandhi N, Chettiar ST, Aziz K, Gajula RP, Williams RD, Kumar R, Taparra K, Zeng J, Cades JA, Velarde E, Menon S, Geschwind JF, Cosgrove D, Pawlik TM, Maitra A, Wong J, Hales RK, Torbenson MS, Herman JM, Tran PT. Wild AT, et al. Among authors: cades ja. PLoS One. 2013 Jun 6;8(6):e65726. doi: 10.1371/journal.pone.0065726. Print 2013. PLoS One. 2013. PMID: 23762417 Free PMC article.
Ganetespib radiosensitization for liver cancer therapy.
Chettiar ST, Malek R, Annadanam A, Nugent KM, Kato Y, Wang H, Cades JA, Taparra K, Belcaid Z, Ballew M, Manmiller S, Proia D, Lim M, Anders RA, Herman JM, Tran PT. Chettiar ST, et al. Among authors: cades ja. Cancer Biol Ther. 2016 Apr 2;17(4):457-66. doi: 10.1080/15384047.2016.1156258. Cancer Biol Ther. 2016. PMID: 26980196 Free PMC article.
A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer.
Yochum ZA, Cades J, Mazzacurati L, Neumann NM, Khetarpal SK, Chatterjee S, Wang H, Attar MA, Huang EH, Chatley SN, Nugent K, Somasundaram A, Engh JA, Ewald AJ, Cho YJ, Rudin CM, Tran PT, Burns TF. Yochum ZA, et al. Among authors: cades j. Mol Cancer Res. 2017 Dec;15(12):1764-1776. doi: 10.1158/1541-7786.MCR-17-0298. Epub 2017 Aug 29. Mol Cancer Res. 2017. PMID: 28851812 Free PMC article.
A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.
Gilbert TM, McDaniel SL, Byrum SD, Cades JA, Dancy BC, Wade H, Tackett AJ, Strahl BD, Taverna SD. Gilbert TM, et al. Among authors: cades ja. Mol Cell Proteomics. 2014 Nov;13(11):2883-95. doi: 10.1074/mcp.M114.038224. Epub 2014 Aug 6. Mol Cell Proteomics. 2014. PMID: 25104842 Free PMC article.