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Plasma cells require autophagy for sustainable immunoglobulin production.
Pengo N, Scolari M, Oliva L, Milan E, Mainoldi F, Raimondi A, Fagioli C, Merlini A, Mariani E, Pasqualetto E, Orfanelli U, Ponzoni M, Sitia R, Casola S, Cenci S. Pengo N, et al. Among authors: casola s. Nat Immunol. 2013 Mar;14(3):298-305. doi: 10.1038/ni.2524. Epub 2013 Jan 27. Nat Immunol. 2013. PMID: 23354484
Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.
Caganova M, Carrisi C, Varano G, Mainoldi F, Zanardi F, Germain PL, George L, Alberghini F, Ferrarini L, Talukder AK, Ponzoni M, Testa G, Nojima T, Doglioni C, Kitamura D, Toellner KM, Su IH, Casola S. Caganova M, et al. Among authors: casola s. J Clin Invest. 2013 Dec;123(12):5009-22. doi: 10.1172/JCI70626. Epub 2013 Nov 8. J Clin Invest. 2013. PMID: 24200695 Free PMC article.
SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.
Simonetti G, Bertilaccio MT, Rodriguez TV, Apollonio B, Dagklis A, Rocchi M, Innocenzi A, Casola S, Winkler TH, Nitschke L, Ponzoni M, Caligaris-Cappio F, Ghia P. Simonetti G, et al. Among authors: casola s. Haematologica. 2014 Aug;99(8):1356-64. doi: 10.3324/haematol.2013.100230. Epub 2014 May 23. Haematologica. 2014. PMID: 24859880 Free PMC article.
The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.
Varano G, Raffel S, Sormani M, Zanardi F, Lonardi S, Zasada C, Perucho L, Petrocelli V, Haake A, Lee AK, Bugatti M, Paul U, Van Anken E, Pasqualucci L, Rabadan R, Siebert R, Kempa S, Ponzoni M, Facchetti F, Rajewsky K, Casola S. Varano G, et al. Among authors: casola s. Nature. 2017 Jun 8;546(7657):302-306. doi: 10.1038/nature22353. Epub 2017 May 31. Nature. 2017. PMID: 28562582
B cell receptor signal strength determines B cell fate.
Casola S, Otipoby KL, Alimzhanov M, Humme S, Uyttersprot N, Kutok JL, Carroll MC, Rajewsky K. Casola S, et al. Nat Immunol. 2004 Mar;5(3):317-27. doi: 10.1038/ni1036. Epub 2004 Feb 1. Nat Immunol. 2004. PMID: 14758357
An epigenetic view of B-cell disorders.
Alberghini F, Petrocelli V, Rahmat M, Casola S. Alberghini F, et al. Among authors: casola s. Immunol Cell Biol. 2015 Mar;93(3):253-60. doi: 10.1038/icb.2014.116. Epub 2015 Jan 20. Immunol Cell Biol. 2015. PMID: 25601271 Review.
63 results