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The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.
Lecca D, Trincavelli ML, Gelosa P, Sironi L, Ciana P, Fumagalli M, Villa G, Verderio C, Grumelli C, Guerrini U, Tremoli E, Rosa P, Cuboni S, Martini C, Buffo A, Cimino M, Abbracchio MP. Lecca D, et al. Among authors: cuboni s. PLoS One. 2008;3(10):e3579. doi: 10.1371/journal.pone.0003579. Epub 2008 Oct 31. PLoS One. 2008. PMID: 18974869 Free PMC article.
Selective inhibitors of the FK506-binding protein 51 by induced fit.
Gaali S, Kirschner A, Cuboni S, Hartmann J, Kozany C, Balsevich G, Namendorf C, Fernandez-Vizarra P, Sippel C, Zannas AS, Draenert R, Binder EB, Almeida OF, Rühter G, Uhr M, Schmidt MV, Touma C, Bracher A, Hausch F. Gaali S, et al. Among authors: cuboni s. Nat Chem Biol. 2015 Jan;11(1):33-7. doi: 10.1038/nchembio.1699. Epub 2014 Dec 1. Nat Chem Biol. 2015. PMID: 25436518
Biomimetic screening of class-B G protein-coupled receptors.
Devigny C, Perez-Balderas F, Hoogeland B, Cuboni S, Wachtel R, Mauch CP, Webb KJ, Deussing JM, Hausch F. Devigny C, et al. Among authors: cuboni s. J Am Chem Soc. 2011 Jun 15;133(23):8927-33. doi: 10.1021/ja200160s. Epub 2011 May 23. J Am Chem Soc. 2011. PMID: 21534574
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