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Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis.
Huang LS, Berdyshev E, Mathew B, Fu P, Gorshkova IA, He D, Ma W, Noth I, Ma SF, Pendyala S, Reddy SP, Zhou T, Zhang W, Garzon SA, Garcia JG, Natarajan V. Huang LS, et al. Among authors: zhou t. FASEB J. 2013 Apr;27(4):1749-60. doi: 10.1096/fj.12-219634. Epub 2013 Jan 11. FASEB J. 2013. PMID: 23315259 Free PMC article.
The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis.
Huang LS, Mathew B, Li H, Zhao Y, Ma SF, Noth I, Reddy SP, Harijith A, Usatyuk PV, Berdyshev EV, Kaminski N, Zhou T, Zhang W, Zhang Y, Rehman J, Kotha SR, Gurney TO, Parinandi NL, Lussier YA, Garcia JG, Natarajan V. Huang LS, et al. Among authors: zhou t. Am J Respir Crit Care Med. 2014 Jun 1;189(11):1402-15. doi: 10.1164/rccm.201310-1917OC. Am J Respir Crit Care Med. 2014. PMID: 24779708 Free PMC article.
Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy.
Huang LS, Berdyshev EV, Tran JT, Xie L, Chen J, Ebenezer DL, Mathew B, Gorshkova I, Zhang W, Reddy SP, Harijith A, Wang G, Feghali-Bostwick C, Noth I, Ma SF, Zhou T, Ma W, Garcia JG, Natarajan V. Huang LS, et al. Among authors: zhou t. Thorax. 2015 Dec;70(12):1138-48. doi: 10.1136/thoraxjnl-2014-206684. Epub 2015 Aug 18. Thorax. 2015. PMID: 26286721 Free article.
Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.
Mathew B, Jacobson JR, Berdyshev E, Huang Y, Sun X, Zhao Y, Gerhold LM, Siegler J, Evenoski C, Wang T, Zhou T, Zaidi R, Moreno-Vinasco L, Bittman R, Chen CT, LaRiviere PJ, Sammani S, Lussier YA, Dudek SM, Natarajan V, Weichselbaum RR, Garcia JG. Mathew B, et al. Among authors: zhou t. FASEB J. 2011 Oct;25(10):3388-400. doi: 10.1096/fj.11-183970. Epub 2011 Jun 28. FASEB J. 2011. PMID: 21712494 Free PMC article.
Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
Gorshkova I, Zhou T, Mathew B, Jacobson JR, Takekoshi D, Bhattacharya P, Smith B, Aydogan B, Weichselbaum RR, Natarajan V, Garcia JG, Berdyshev EV. Gorshkova I, et al. Among authors: zhou t. J Lipid Res. 2012 Aug;53(8):1553-68. doi: 10.1194/jlr.M026039. Epub 2012 May 21. J Lipid Res. 2012. PMID: 22615416 Free PMC article.
Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis.
Huang Y, Ma SF, Espindola MS, Vij R, Oldham JM, Huffnagle GB, Erb-Downward JR, Flaherty KR, Moore BB, White ES, Zhou T, Li J, Lussier YA, Han MK, Kaminski N, Garcia JGN, Hogaboam CM, Martinez FJ, Noth I; COMET-IPF Investigators. Huang Y, et al. Among authors: zhou t. Am J Respir Crit Care Med. 2017 Jul 15;196(2):208-219. doi: 10.1164/rccm.201607-1525OC. Am J Respir Crit Care Med. 2017. PMID: 28157391 Free PMC article.
Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury.
Sun X, Singleton PA, Letsiou E, Zhao J, Belvitch P, Sammani S, Chiang ET, Moreno-Vinasco L, Wade MS, Zhou T, Liu B, Parastatidis I, Thomson L, Ischiropoulos H, Natarajan V, Jacobson JR, Machado RF, Dudek SM, Garcia JG. Sun X, et al. Among authors: zhou t. Am J Respir Cell Mol Biol. 2012 Nov;47(5):628-36. doi: 10.1165/rcmb.2012-0048OC. Epub 2012 Jul 5. Am J Respir Cell Mol Biol. 2012. PMID: 22771388 Free PMC article.
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