Arce PM - Search Results

1

Effects of cytoprotective antioxidants on lymphocytes from representative mitochondrial neurodegenerative diseases.

Goldschmidt R, Arce PM, Khdour OM, Collin VC, Dey S, Jaruvangsanti J, Fash DM, Hecht SM. Goldschmidt R, et al. Among authors: arce pm. Bioorg Med Chem. 2013 Feb 15;21(4):969-78. doi: 10.1016/j.bmc.2012.11.051. Epub 2012 Dec 12. Bioorg Med Chem. 2013. PMID: 23313093

2

Synthesis and characterization of mitoQ and idebenone analogues as mediators of oxygen consumption in mitochondria.

Duveau DY, Arce PM, Schoenfeld RA, Raghav N, Cortopassi GA, Hecht SM. Duveau DY, et al. Among authors: arce pm. Bioorg Med Chem. 2010 Sep 1;18(17):6429-41. doi: 10.1016/j.bmc.2010.06.104. Epub 2010 Aug 4. Bioorg Med Chem. 2010. PMID: 20691600 Free PMC article.

3

Analysis of the structural and mechanistic factors in antioxidants that preserve mitochondrial function and confer cytoprotection.

Arce PM, Goldschmidt R, Khdour OM, Madathil MM, Jaruvangsanti J, Dey S, Fash DM, Armstrong JS, Hecht SM. Arce PM, et al. Bioorg Med Chem. 2012 Sep 1;20(17):5188-201. doi: 10.1016/j.bmc.2012.07.005. Epub 2012 Jul 14. Bioorg Med Chem. 2012. PMID: 22883028

4

Effects of alkyl side chain modification of coenzyme Q10 on mitochondrial respiratory chain function and cytoprotection.

Fash DM, Khdour OM, Sahdeo SJ, Goldschmidt R, Jaruvangsanti J, Dey S, Arce PM, Collin VC, Cortopassi GA, Hecht SM. Fash DM, et al. Among authors: arce pm. Bioorg Med Chem. 2013 Apr 15;21(8):2346-2354. doi: 10.1016/j.bmc.2013.01.075. Epub 2013 Feb 13. Bioorg Med Chem. 2013. PMID: 23473946

5

A Strategy for Suppressing Redox Stress within Mitochondria.

Arce PM, Khdour OM, Goldschmidt R, Armstrong JS, Hecht SM. Arce PM, et al. ACS Med Chem Lett. 2011 May 31;2(8):608-13. doi: 10.1021/ml200095w. eCollection 2011 Aug 11. ACS Med Chem Lett. 2011. PMID: 24900356 Free PMC article.

6

An optimized pyrimidinol multifunctional radical quencher.

Khdour OM, Arce PM, Roy B, Hecht SM. Khdour OM, et al. Among authors: arce pm. ACS Med Chem Lett. 2013 May 28;4(8):724-9. doi: 10.1021/ml400130z. eCollection 2013 Aug 8. ACS Med Chem Lett. 2013. PMID: 24900738 Free PMC article.

7

Cytoprotective pyridinol antioxidants as potential therapeutic agents for neurodegenerative and mitochondrial diseases.

Alam MP, Khdour OM, Arce PM, Chen Y, Roy B, Johnson WG, Dey S, Hecht SM. Alam MP, et al. Among authors: arce pm. Bioorg Med Chem. 2014 Sep 1;22(17):4935-47. doi: 10.1016/j.bmc.2014.06.040. Epub 2014 Jun 28. Bioorg Med Chem. 2014. PMID: 25088548

8

Novel antioxidants protect mitochondria from the effects of oligomeric amyloid beta and contribute to the maintenance of epigenome function.

Mastroeni D, Khdour OM, Arce PM, Hecht SM, Coleman PD. Mastroeni D, et al. Among authors: arce pm. ACS Chem Neurosci. 2015 Apr 15;6(4):588-98. doi: 10.1021/cn500323q. Epub 2015 Feb 24. ACS Chem Neurosci. 2015. PMID: 25668062 Free PMC article.

9

Optimization of pyrimidinol antioxidants as mitochondrial protective agents: ATP production and metabolic stability.

Chevalier A, Alam MP, Khdour OM, Schmierer M, Arce PM, Cripe CD, Hecht SM. Chevalier A, et al. Among authors: arce pm. Bioorg Med Chem. 2016 Nov 1;24(21):5206-5220. doi: 10.1016/j.bmc.2016.08.039. Epub 2016 Aug 23. Bioorg Med Chem. 2016. PMID: 27624526

10

Efficient asymmetric synthesis of tryptophan analogues having useful photophysical properties.

Talukder P, Chen S, Arce PM, Hecht SM. Talukder P, et al. Among authors: arce pm. Org Lett. 2014 Jan 17;16(2):556-9. doi: 10.1021/ol403429e. Epub 2014 Jan 6. Org Lett. 2014. PMID: 24392870 Free PMC article.

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