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Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein.
Sauter D, Unterweger D, Vogl M, Usmani SM, Heigele A, Kluge SF, Hermkes E, Moll M, Barker E, Peeters M, Learn GH, Bibollet-Ruche F, Fritz JV, Fackler OT, Hahn BH, Kirchhoff F. Sauter D, et al. Among authors: hermkes e. PLoS Pathog. 2012 Dec;8(12):e1003093. doi: 10.1371/journal.ppat.1003093. Epub 2012 Dec 20. PLoS Pathog. 2012. PMID: 23308067 Free PMC article.
The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein.
Walliser C, Hermkes E, Schade A, Wiese S, Deinzer J, Zapatka M, Désiré L, Mertens D, Stilgenbauer S, Gierschik P. Walliser C, et al. Among authors: hermkes e. J Biol Chem. 2016 Oct 14;291(42):22136-22148. doi: 10.1074/jbc.M116.746842. Epub 2016 Aug 19. J Biol Chem. 2016. PMID: 27542411 Free PMC article.
Functional characterization of phospholipase C-γ2 mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder.
Walliser C, Wist M, Hermkes E, Zhou Y, Schade A, Haas J, Deinzer J, Désiré L, Li SSC, Stilgenbauer S, Milner JD, Gierschik P. Walliser C, et al. Among authors: hermkes e. Oncotarget. 2018 Sep 28;9(76):34357-34378. doi: 10.18632/oncotarget.26173. eCollection 2018 Sep 28. Oncotarget. 2018. PMID: 30344948 Free PMC article.