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[An approach for anti-fibrotic drug discovery in NASH].
Sudoh M, Matsumoto M. Sudoh M, et al. Nihon Yakurigaku Zasshi. 2014 Aug;144(2):69-74. doi: 10.1254/fpj.144.69. Nihon Yakurigaku Zasshi. 2014. PMID: 25109519 Japanese. No abstract available.
An orally available, small-molecule interferon inhibits viral replication.
Konishi H, Okamoto K, Ohmori Y, Yoshino H, Ohmori H, Ashihara M, Hirata Y, Ohta A, Sakamoto H, Hada N, Katsume A, Kohara M, Morikawa K, Tsukuda T, Shimma N, Foster GR, Alazawi W, Aoki Y, Arisawa M, Sudoh M. Konishi H, et al. Among authors: sudoh m. Sci Rep. 2012;2:259. doi: 10.1038/srep00259. Epub 2012 Feb 10. Sci Rep. 2012. PMID: 22355771 Free PMC article.
Host sphingolipid biosynthesis as a target for hepatitis C virus therapy.
Sakamoto H, Okamoto K, Aoki M, Kato H, Katsume A, Ohta A, Tsukuda T, Shimma N, Aoki Y, Arisawa M, Kohara M, Sudoh M. Sakamoto H, et al. Among authors: sudoh m. Nat Chem Biol. 2005 Nov;1(6):333-7. doi: 10.1038/nchembio742. Epub 2005 Oct 16. Nat Chem Biol. 2005. PMID: 16408072
A serine palmitoyltransferase inhibitor blocks hepatitis C virus replication in human hepatocytes.
Katsume A, Tokunaga Y, Hirata Y, Munakata T, Saito M, Hayashi H, Okamoto K, Ohmori Y, Kusanagi I, Fujiwara S, Tsukuda T, Aoki Y, Klumpp K, Tsukiyama-Kohara K, El-Gohary A, Sudoh M, Kohara M. Katsume A, et al. Among authors: sudoh m. Gastroenterology. 2013 Oct;145(4):865-73. doi: 10.1053/j.gastro.2013.06.012. Epub 2013 Jun 18. Gastroenterology. 2013. PMID: 23791700 Free article.
Enantioselective synthesis of derivatives and structure-activity relationship study in the development of NA255 as a novel host-targeting anti-HCV agent.
Kawasaki K, Masubuchi M, Hayase T, Komiyama S, Watanabe F, Fukuda H, Murata T, Matsubara Y, Koyama K, Shindoh H, Sakamoto H, Okamato K, Ohta A, Katsume A, Aoki M, Aoki Y, Shimma N, Sudoh M, Tsukuda T. Kawasaki K, et al. Among authors: sudoh m. Bioorg Med Chem Lett. 2013 Jan 1;23(1):336-9. doi: 10.1016/j.bmcl.2012.10.083. Epub 2012 Oct 30. Bioorg Med Chem Lett. 2013. PMID: 23164713
Self-enhancement of hepatitis C virus replication by promotion of specific sphingolipid biosynthesis.
Hirata Y, Ikeda K, Sudoh M, Tokunaga Y, Suzuki A, Weng L, Ohta M, Tobita Y, Okano K, Ozeki K, Kawasaki K, Tsukuda T, Katsume A, Aoki Y, Umehara T, Sekiguchi S, Toyoda T, Shimotohno K, Soga T, Nishijima M, Taguchi R, Kohara M. Hirata Y, et al. Among authors: sudoh m. PLoS Pathog. 2012;8(8):e1002860. doi: 10.1371/journal.ppat.1002860. Epub 2012 Aug 16. PLoS Pathog. 2012. PMID: 22916015 Free PMC article.
A novel nonsecosteroidal VDR agonist (CH5036249) exhibits efficacy in a spontaneous benign prostatic hyperplasia beagle model.
Taniguchi K, Katagiri K, Kashiwagi H, Harada S, Sugimoto Y, Shimizu Y, Arakawa H, Ito T, Yamazaki M, Watanabe T, Kato A, Hoshino E, Takahashi T, Esaki T, Suzuki M, Takeda S, Ichikawa F, Harada A, Sekiguchi N, Ishigai M, Kawata H, Yoneya T, Onuma E, Sudoh M, Aoki Y. Taniguchi K, et al. Among authors: sudoh m. J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):204-7. doi: 10.1016/j.jsbmb.2010.03.043. Epub 2010 Mar 18. J Steroid Biochem Mol Biol. 2010. PMID: 20304062
Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice.
Tateno C, Kawase Y, Tobita Y, Hamamura S, Ohshita H, Yokomichi H, Sanada H, Kakuni M, Shiota A, Kojima Y, Ishida Y, Shitara H, Wada NA, Tateishi H, Sudoh M, Nagatsuka S, Jishage K, Kohara M. Tateno C, et al. Among authors: sudoh m. PLoS One. 2015 Nov 4;10(11):e0142145. doi: 10.1371/journal.pone.0142145. eCollection 2015. PLoS One. 2015. PMID: 26536627 Free PMC article.
106 results