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Latent regulatory potential of human-specific repetitive elements.
Ward MC, Wilson MD, Barbosa-Morais NL, Schmidt D, Stark R, Pan Q, Schwalie PC, Menon S, Lukk M, Watt S, Thybert D, Kutter C, Kirschner K, Flicek P, Blencowe BJ, Odom DT. Ward MC, et al. Among authors: kirschner k. Mol Cell. 2013 Jan 24;49(2):262-72. doi: 10.1016/j.molcel.2012.11.013. Epub 2012 Dec 13. Mol Cell. 2013. PMID: 23246434 Free PMC article.
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.
Chandra T, Kirschner K, Thuret JY, Pope BD, Ryba T, Newman S, Ahmed K, Samarajiwa SA, Salama R, Carroll T, Stark R, Janky R, Narita M, Xue L, Chicas A, Nũnez S, Janknecht R, Hayashi-Takanaka Y, Wilson MD, Marshall A, Odom DT, Babu MM, Bazett-Jones DP, Tavaré S, Edwards PA, Lowe SW, Kimura H, Gilbert DM, Narita M. Chandra T, et al. Among authors: kirschner k. Mol Cell. 2012 Jul 27;47(2):203-14. doi: 10.1016/j.molcel.2012.06.010. Epub 2012 Jul 12. Mol Cell. 2012. PMID: 22795131 Free PMC article.
Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53.
Kirschner K, Samarajiwa SA, Cairns JM, Menon S, Pérez-Mancera PA, Tomimatsu K, Bermejo-Rodriguez C, Ito Y, Chandra T, Narita M, Lyons SK, Lynch AG, Kimura H, Ohbayashi T, Tavaré S, Narita M. Kirschner K, et al. PLoS Genet. 2015 Mar 19;11(3):e1005053. doi: 10.1371/journal.pgen.1005053. eCollection 2015 Mar. PLoS Genet. 2015. PMID: 25790137 Free PMC article.
Global reorganization of the nuclear landscape in senescent cells.
Chandra T, Ewels PA, Schoenfelder S, Furlan-Magaril M, Wingett SW, Kirschner K, Thuret JY, Andrews S, Fraser P, Reik W. Chandra T, et al. Among authors: kirschner k. Cell Rep. 2015 Feb 3;10(4):471-83. doi: 10.1016/j.celrep.2014.12.055. Epub 2015 Jan 29. Cell Rep. 2015. PMID: 25640177 Free PMC article.
Chromosome organisation during ageing and senescence.
Chandra T, Kirschner K. Chandra T, et al. Among authors: kirschner k. Curr Opin Cell Biol. 2016 Jun;40:161-167. doi: 10.1016/j.ceb.2016.03.020. Epub 2016 Apr 19. Curr Opin Cell Biol. 2016. PMID: 27101466 Free article. Review.
Notch Signaling Mediates Secondary Senescence.
Teo YV, Rattanavirotkul N, Olova N, Salzano A, Quintanilla A, Tarrats N, Kiourtis C, Müller M, Green AR, Adams PD, Acosta JC, Bird TG, Kirschner K, Neretti N, Chandra T. Teo YV, et al. Among authors: kirschner k. Cell Rep. 2019 Apr 23;27(4):997-1007.e5. doi: 10.1016/j.celrep.2019.03.104. Cell Rep. 2019. PMID: 31018144 Free PMC article.
Autophagy mediates the mitotic senescence transition.
Young AR, Narita M, Ferreira M, Kirschner K, Sadaie M, Darot JF, Tavaré S, Arakawa S, Shimizu S, Watt FM, Narita M. Young AR, et al. Among authors: kirschner k. Genes Dev. 2009 Apr 1;23(7):798-803. doi: 10.1101/gad.519709. Epub 2009 Mar 11. Genes Dev. 2009. PMID: 19279323 Free PMC article.
319 results