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LRP5 and LRP6 in development and disease.
Joiner DM, Ke J, Zhong Z, Xu HE, Williams BO. Joiner DM, et al. Trends Endocrinol Metab. 2013 Jan;24(1):31-9. doi: 10.1016/j.tem.2012.10.003. Trends Endocrinol Metab. 2013. PMID: 23245947 Free PMC article. Review.
Loss of BMP signaling mediated by BMPR1A in osteoblasts leads to differential bone phenotypes in mice depending on anatomical location of the bones.
Zhang H, Zhang Y, Terajima M, Romanowicz G, Liu Y, Omi M, Bigelow E, Joiner DM, Waldorff EI, Zhu P, Raghavan M, Lynch M, Kamiya N, Zhang R, Jepsen KJ, Goldstein S, Morris MD, Yamauchi M, Kohn DH, Mishina Y. Zhang H, et al. Among authors: joiner dm. Bone. 2020 Aug;137:115402. doi: 10.1016/j.bone.2020.115402. Epub 2020 May 1. Bone. 2020. PMID: 32360900 Free PMC article.
Bone mass is inversely proportional to Dkk1 levels in mice.
MacDonald BT, Joiner DM, Oyserman SM, Sharma P, Goldstein SA, He X, Hauschka PV. MacDonald BT, et al. Among authors: joiner dm. Bone. 2007 Sep;41(3):331-9. doi: 10.1016/j.bone.2007.05.009. Epub 2007 Jun 5. Bone. 2007. PMID: 17613296 Free PMC article.
Controversy of physiological vs. pharmacological effects of BMP signaling: Constitutive activation of BMP type IA receptor-dependent signaling in osteoblast lineage enhances bone formation and resorption, not affecting net bone mass.
Kamiya N, Atsawasuwan P, Joiner DM, Waldorff EI, Goldstein S, Yamauchi M, Mishina Y. Kamiya N, et al. Among authors: joiner dm. Bone. 2020 Sep;138:115513. doi: 10.1016/j.bone.2020.115513. Epub 2020 Jun 27. Bone. 2020. PMID: 32603910 Free PMC article.
Hypercholesterolemia promotes an osteoporotic phenotype.
Pelton K, Krieder J, Joiner D, Freeman MR, Goldstein SA, Solomon KR. Pelton K, et al. Am J Pathol. 2012 Sep;181(3):928-36. doi: 10.1016/j.ajpath.2012.05.034. Epub 2012 Jul 4. Am J Pathol. 2012. PMID: 22770664 Free PMC article.
11 results