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VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway.
Lee C, Chen R, Sun G, Liu X, Lin X, He C, Xing L, Liu L, Jensen LD, Kumar A, Langer HF, Ren X, Zhang J, Huang L, Yin X, Kim J, Zhu J, Huang G, Li J, Lu W, Chen W, Liu J, Hu J, Sun Q, Lu W, Fang L, Wang S, Kuang H, Zhang Y, Tian G, Mi J, Kang BA, Narazaki M, Prodeus A, Schoonjans L, Ornitz DM, Gariepy J, Eelen G, Dewerchin M, Yang Y, Ou JS, Mora A, Yao J, Zhao C, Liu Y, Carmeliet P, Cao Y, Li X. Lee C, et al. Among authors: eelen g. Signal Transduct Target Ther. 2023 Aug 18;8(1):305. doi: 10.1038/s41392-023-01539-9. Signal Transduct Target Ther. 2023. PMID: 37591843 Free PMC article.
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells.
Sneyers F, Kerkhofs M, Speelman-Rooms F, Welkenhuyzen K, La Rovere R, Shemy A, Voet A, Eelen G, Dewerchin M, Tait SWG, Ghesquière B, Bootman MD, Bultynck G. Sneyers F, et al. Among authors: eelen g. Cell Death Dis. 2023 Sep 8;14(9):600. doi: 10.1038/s41419-023-06120-4. Cell Death Dis. 2023. PMID: 37684238 Free PMC article.
Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity.
Verlinden L, Verstuyf A, Verboven C, Eelen G, De Ranter C, Gao LJ, Chen YJ, Murad I, Choi M, Yamamoto K, Yamada S, Van Haver D, Vandewalle M, De Clercq PJ, Bouillon R. Verlinden L, et al. Among authors: eelen g. J Biol Chem. 2003 Sep 12;278(37):35476-82. doi: 10.1074/jbc.M302045200. Epub 2003 Jun 26. J Biol Chem. 2003. PMID: 12829710 Free article.
90 results