Wells RD - Search Results

1

Expanded complexity of unstable repeat diseases.

Polak U, McIvor E, Dent SY, Wells RD, Napierala M. Polak U, et al. Among authors: wells rd. Biofactors. 2013 Mar-Apr;39(2):164-75. doi: 10.1002/biof.1060. Epub 2012 Dec 11. Biofactors. 2013. PMID: 23233240 Free PMC article. Review.

2

Advances in mechanisms of genetic instability related to hereditary neurological diseases.

Wells RD, Dere R, Hebert ML, Napierala M, Son LS. Wells RD, et al. Nucleic Acids Res. 2005 Jul 8;33(12):3785-98. doi: 10.1093/nar/gki697. Print 2005. Nucleic Acids Res. 2005. PMID: 16006624 Free PMC article. Review.

3

Increased negative superhelical density in vivo enhances the genetic instability of triplet repeat sequences.

Napierala M, Bacolla A, Wells RD. Napierala M, et al. Among authors: wells rd. J Biol Chem. 2005 Nov 11;280(45):37366-76. doi: 10.1074/jbc.M508065200. Epub 2005 Sep 13. J Biol Chem. 2005. PMID: 16166072 Free article.

4

R loops stimulate genetic instability of CTG.CAG repeats.

Lin Y, Dent SY, Wilson JH, Wells RD, Napierala M. Lin Y, et al. Among authors: wells rd. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):692-7. doi: 10.1073/pnas.0909740107. Epub 2009 Dec 22. Proc Natl Acad Sci U S A. 2010. PMID: 20080737 Free PMC article.

5

Long CTG.CAG repeat sequences markedly stimulate intramolecular recombination.

Napierala M, Parniewski P, Pluciennik A, Wells RD. Napierala M, et al. Among authors: wells rd. J Biol Chem. 2002 Sep 13;277(37):34087-100. doi: 10.1074/jbc.M202128200. Epub 2002 Jun 3. J Biol Chem. 2002. PMID: 12045198 Free article.

6

Non-B DNA conformations formed by long repeating tracts of myotonic dystrophy type 1, myotonic dystrophy type 2, and Friedreich's ataxia genes, not the sequences per se, promote mutagenesis in flanking regions.

Wojciechowska M, Napierala M, Larson JE, Wells RD. Wojciechowska M, et al. Among authors: wells rd. J Biol Chem. 2006 Aug 25;281(34):24531-43. doi: 10.1074/jbc.M603888200. Epub 2006 Jun 21. J Biol Chem. 2006. PMID: 16793772 Free article.

7

DNA triplet repeat expansion and mismatch repair.

Iyer RR, Pluciennik A, Napierala M, Wells RD. Iyer RR, et al. Among authors: wells rd. Annu Rev Biochem. 2015;84:199-226. doi: 10.1146/annurev-biochem-060614-034010. Epub 2015 Jan 2. Annu Rev Biochem. 2015. PMID: 25580529 Free PMC article. Review.

8

Long CTG.CAG repeats from myotonic dystrophy are preferred sites for intermolecular recombination.

Pluciennik A, Iyer RR, Napierala M, Larson JE, Filutowicz M, Wells RD. Pluciennik A, et al. Among authors: wells rd. J Biol Chem. 2002 Sep 13;277(37):34074-86. doi: 10.1074/jbc.M202127200. Epub 2002 Jun 26. J Biol Chem. 2002. PMID: 12087090 Free article.

9

Structure-dependent recombination hot spot activity of GAA.TTC sequences from intron 1 of the Friedreich's ataxia gene.

Napierala M, Dere R, Vetcher A, Wells RD. Napierala M, et al. Among authors: wells rd. J Biol Chem. 2004 Feb 20;279(8):6444-54. doi: 10.1074/jbc.M309596200. Epub 2003 Nov 18. J Biol Chem. 2004. PMID: 14625270 Free article.

10

Long intronic GAA*TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia.

Soragni E, Herman D, Dent SY, Gottesfeld JM, Wells RD, Napierala M. Soragni E, et al. Among authors: wells rd. Nucleic Acids Res. 2008 Nov;36(19):6056-65. doi: 10.1093/nar/gkn604. Epub 2008 Sep 27. Nucleic Acids Res. 2008. PMID: 18820300 Free PMC article.

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