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Dual Axl/MerTK inhibitor INCB081776 creates a proinflammatory tumor immune microenvironment and enhances anti-PDL1 efficacy in head and neck cancer.
Kostecki KL, Iida M, Wiley AL, Kimani S, Mehall B, Tetreault K, Alexandridis R, Yu M, Hong S, Salgia R, Bruce JY, Birge RB, Harari PM, Wheeler DL. Kostecki KL, et al. Among authors: birge rb. Head Neck. 2023 May;45(5):1255-1271. doi: 10.1002/hed.27340. Epub 2023 Mar 20. Head Neck. 2023. PMID: 36939040 Free PMC article.
Mertk: An emerging target in cancer biology and immuno-oncology.
Lahey KC, Gadiyar V, Hill A, Desind S, Wang Z, Davra V, Patel R, Zaman A, Calianese D, Birge RB. Lahey KC, et al. Among authors: birge rb. Int Rev Cell Mol Biol. 2022;368:35-59. doi: 10.1016/bs.ircmb.2022.04.004. Epub 2022 May 5. Int Rev Cell Mol Biol. 2022. PMID: 35636929 Free PMC article.
Phosphatidylserine-Targeting Monoclonal Antibodies Exhibit Distinct Biochemical and Cellular Effects on Anti-CD3/CD28-Stimulated T Cell IFN-γ and TNF-α Production.
Calianese D, Kreiss T, Kasikara C, Davra V, Lahey KC, Gadiyar V, Geng K, Singh S, Honnen W, Jaijyan DK, Reichman C, Siekierka J, Gennaro ML, Kotenko SV, Ucker DS, Brekken RA, Pinter A, Birge RB, Choudhary A. Calianese D, et al. Among authors: birge rb. J Immunol. 2021 Jul 15;207(2):436-448. doi: 10.4049/jimmunol.2000763. Epub 2021 Jul 2. J Immunol. 2021. PMID: 34215655
113 results