Cappello M - Search Results

1

A furoxan-amodiaquine hybrid as a potential therapeutic for three parasitic diseases().

Mott BT, Cheng KC, Guha R, Kommer VP, Williams DL, Vermeire JJ, Cappello M, Maloney DJ, Rai G, Jadhav A, Simeonov A, Inglese J, Posner GH, Thomas CJ. Mott BT, et al. Among authors: cappello m. Medchemcomm. 2012 Dec;3(12):1505-1511. doi: 10.1039/C2MD20238G. Medchemcomm. 2012. PMID: 23205265 Free PMC article.

2

In vitro screening of compounds against laboratory and field isolates of human hookworm reveals quantitative differences in anthelmintic susceptibility.

Treger RS, Otchere J, Keil MF, Quagraine JE, Rai G, Mott BT, Humphries DL, Wilson M, Cappello M, Vermeire JJ. Treger RS, et al. Among authors: cappello m. Am J Trop Med Hyg. 2014 Jan;90(1):71-4. doi: 10.4269/ajtmh.12-0547. Epub 2013 Dec 2. Am J Trop Med Hyg. 2014. PMID: 24297811 Free PMC article.

3

Oxadiazole 2-oxides are toxic to the human hookworm, Ancylostoma ceylanicum, however glutathione reductase is not the primary target.

Treger RS, Cook AG, Rai G, Maloney DJ, Simeonov A, Jadhav A, Thomas CJ, Williams DL, Cappello M, Vermeire JJ. Treger RS, et al. Among authors: cappello m. Int J Parasitol Drugs Drug Resist. 2012 Dec 1;2:171-177. doi: 10.1016/j.ijpddr.2012.05.001. Epub 2012 May 18. Int J Parasitol Drugs Drug Resist. 2012. PMID: 22844653 Free PMC article.

4

Peroxiredoxin-1 from the human hookworm Ancylostoma ceylanicum forms a stable oxidized decamer and is covalently inhibited by conoidin A.

Nguyen JB, Pool CD, Wong CY, Treger RS, Williams DL, Cappello M, Lea WA, Simeonov A, Vermeire JJ, Modis Y. Nguyen JB, et al. Among authors: cappello m. Chem Biol. 2013 Aug 22;20(8):991-1001. doi: 10.1016/j.chembiol.2013.06.011. Epub 2013 Jul 25. Chem Biol. 2013. PMID: 23891152 Free PMC article.

5

Orthologs of macrophage migration inhibitory factor from parasitic nematodes.

Vermeire JJ, Cho Y, Lolis E, Bucala R, Cappello M. Vermeire JJ, et al. Among authors: cappello m. Trends Parasitol. 2008 Aug;24(8):355-63. doi: 10.1016/j.pt.2008.04.007. Epub 2008 Jul 4. Trends Parasitol. 2008. PMID: 18603473 Free PMC article. Review.

6

Characterisation of a fatty acid and retinol binding protein orthologue from the hookworm Ancylostoma ceylanicum.

Fairfax KC, Vermeire JJ, Harrison LM, Bungiro RD, Grant W, Husain SZ, Cappello M. Fairfax KC, et al. Among authors: cappello m. Int J Parasitol. 2009 Dec;39(14):1561-71. doi: 10.1016/j.ijpara.2009.06.005. Epub 2009 Jul 8. Int J Parasitol. 2009. PMID: 19591834 Free PMC article.

7

Drug repositioning and pharmacophore identification in the discovery of hookworm MIF inhibitors.

Cho Y, Vermeire JJ, Merkel JS, Leng L, Du X, Bucala R, Cappello M, Lolis E. Cho Y, et al. Among authors: cappello m. Chem Biol. 2011 Sep 23;18(9):1089-101. doi: 10.1016/j.chembiol.2011.07.011. Chem Biol. 2011. PMID: 21944748 Free PMC article.

8

Role for nitric oxide in hookworm-associated immune suppression.

Dondji B, Bungiro RD, Harrison LM, Vermeire JJ, Bifulco C, McMahon-Pratt D, Cappello M. Dondji B, et al. Among authors: cappello m. Infect Immun. 2008 Jun;76(6):2560-7. doi: 10.1128/IAI.00094-08. Epub 2008 Mar 17. Infect Immun. 2008. PMID: 18347036 Free PMC article.

9

Structural and functional characterization of a secreted hookworm Macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74.

Cho Y, Jones BF, Vermeire JJ, Leng L, DiFedele L, Harrison LM, Xiong H, Kwong YK, Chen Y, Bucala R, Lolis E, Cappello M. Cho Y, et al. Among authors: cappello m. J Biol Chem. 2007 Aug 10;282(32):23447-56. doi: 10.1074/jbc.M702950200. Epub 2007 Jun 13. J Biol Chem. 2007. PMID: 17567581 Free PMC article.

10

Frequency and intensity of exposure mediate resistance to experimental infection with the hookworm, Ancylostoma ceylanicum.

Davey D, Manickam N, Simms BT, Harrison LM, Vermeire JJ, Cappello M. Davey D, et al. Among authors: cappello m. Exp Parasitol. 2013 Mar;133(3):243-9. doi: 10.1016/j.exppara.2012.11.010. Epub 2012 Dec 8. Exp Parasitol. 2013. PMID: 23232252 Free PMC article.

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