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Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
Redecke L, Nass K, DePonte DP, White TA, Rehders D, Barty A, Stellato F, Liang M, Barends TRM, Boutet S, Williams GJ, Messerschmidt M, Seibert MM, Aquila A, Arnlund D, Bajt S, Barth T, Bogan MJ, Caleman C, Chao TC, Doak RB, Fleckenstein H, Frank M, Fromme R, Galli L, Grotjohann I, Hunter MS, Johansson LC, Kassemeyer S, Katona G, Kirian RA, Koopmann R, Kupitz C, Lomb L, Martin AV, Mogk S, Neutze R, Shoeman RL, Steinbrener J, Timneanu N, Wang D, Weierstall U, Zatsepin NA, Spence JCH, Fromme P, Schlichting I, Duszenko M, Betzel C, Chapman HN. Redecke L, et al. Among authors: schlichting i. Science. 2013 Jan 11;339(6116):227-230. doi: 10.1126/science.1229663. Epub 2012 Nov 29. Science. 2013. PMID: 23196907 Free PMC article.
The catalytic pathway of cytochrome p450cam at atomic resolution.
Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG. Schlichting I, et al. Science. 2000 Mar 3;287(5458):1615-22. doi: 10.1126/science.287.5458.1615. Science. 2000. PMID: 10698731
Tryptophan synthase: the workings of a channeling nanomachine.
Dunn MF, Niks D, Ngo H, Barends TR, Schlichting I. Dunn MF, et al. Among authors: schlichting i. Trends Biochem Sci. 2008 Jun;33(6):254-64. doi: 10.1016/j.tibs.2008.04.008. Epub 2008 May 15. Trends Biochem Sci. 2008. PMID: 18486479 Review.
Tryptophan synthase, an allosteric molecular factory.
Barends TR, Dunn MF, Schlichting I. Barends TR, et al. Among authors: schlichting i. Curr Opin Chem Biol. 2008 Oct;12(5):593-600. doi: 10.1016/j.cbpa.2008.07.011. Curr Opin Chem Biol. 2008. PMID: 18675375
Crystal structure and mechanism of a DNA (6-4) photolyase.
Maul MJ, Barends TR, Glas AF, Cryle MJ, Domratcheva T, Schneider S, Schlichting I, Carell T. Maul MJ, et al. Among authors: schlichting i. Angew Chem Int Ed Engl. 2008;47(52):10076-80. doi: 10.1002/anie.200804268. Angew Chem Int Ed Engl. 2008. PMID: 18956392 No abstract available.
217 results