Smirnova NA - Search Results

1

Catalytic mechanism and substrate specificity of HIF prolyl hydroxylases.

Smirnova NA, Hushpulian DM, Speer RE, Gaisina IN, Ratan RR, Gazaryan IG. Smirnova NA, et al. Biochemistry (Mosc). 2012 Oct;77(10):1108-19. doi: 10.1134/S0006297912100033. Biochemistry (Mosc). 2012. PMID: 23157291 Free article. Review.

2

Enzyme-Substrate Reporters for Evaluation of Substrate Specificity of HIF Prolyl Hydroxylase Isoforms.

Osipyants AI, Smirnova NA, Khristichenko AY, Hushpulian DM, Nikulin SV, Chubar TA, Zakhariants AA, Tishkov VI, Gazaryan IG, Poloznikov AA. Osipyants AI, et al. Among authors: smirnova na. Biochemistry (Mosc). 2017 Oct;82(10):1207-1214. doi: 10.1134/S0006297917100145. Biochemistry (Mosc). 2017. PMID: 29037142 Free article.

3

Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation.

Smirnova NA, Rakhman I, Moroz N, Basso M, Payappilly J, Kazakov S, Hernandez-Guzman F, Gaisina IN, Kozikowski AP, Ratan RR, Gazaryan IG. Smirnova NA, et al. Chem Biol. 2010 Apr 23;17(4):380-91. doi: 10.1016/j.chembiol.2010.03.008. Chem Biol. 2010. PMID: 20416509 Free PMC article.

4

L-ascorbic acid: A true substrate for HIF prolyl hydroxylase?

Osipyants AI, Poloznikov AA, Smirnova NA, Hushpulian DM, Khristichenko AY, Chubar TA, Zakhariants AA, Ahuja M, Gaisina IN, Thomas B, Brown AM, Gazaryan IG, Tishkov VI. Osipyants AI, et al. Among authors: smirnova na. Biochimie. 2018 Apr;147:46-54. doi: 10.1016/j.biochi.2017.12.011. Epub 2017 Dec 28. Biochimie. 2018. PMID: 29289682 Free PMC article.

5

Structure-activity relationship for branched oxyquinoline HIF activators: Effect of modifications to phenylacetamide "tail".

Poloznikov AA, Zakhariants AA, Nikulin SV, Smirnova NA, Hushpulian DM, Gaisina IN, Tonevitsky AG, Tishkov VI, Gazaryan IG. Poloznikov AA, et al. Among authors: smirnova na. Biochimie. 2017 Feb;133:74-79. doi: 10.1016/j.biochi.2016.12.004. Epub 2016 Dec 19. Biochimie. 2017. PMID: 28007502

6

Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators.

Smirnova NA, Haskew-Layton RE, Basso M, Hushpulian DM, Payappilly JB, Speer RE, Ahn YH, Rakhman I, Cole PA, Pinto JT, Ratan RR, Gazaryan IG. Smirnova NA, et al. Chem Biol. 2011 Jun 24;18(6):752-65. doi: 10.1016/j.chembiol.2011.03.013. Chem Biol. 2011. PMID: 21700211 Free PMC article.

7

In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation.

Karuppagounder SS, Basso M, Sleiman SF, Ma TC, Speer RE, Smirnova NA, Gazaryan IG, Ratan RR. Karuppagounder SS, et al. Among authors: smirnova na. J Neurosci Res. 2013 Aug;91(8):1066-75. doi: 10.1002/jnr.23204. Epub 2013 Mar 4. J Neurosci Res. 2013. PMID: 23456821 Free PMC article.

8

Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease.

Smirnova NA, Kaidery NA, Hushpulian DM, Rakhman II, Poloznikov AA, Tishkov VI, Karuppagounder SS, Gaisina IN, Pekcec A, Leyen KV, Kazakov SV, Yang L, Thomas B, Ratan RR, Gazaryan IG. Smirnova NA, et al. Aging Dis. 2016 Dec 1;7(6):745-762. doi: 10.14336/AD.2016.0505. eCollection 2016 Dec. Aging Dis. 2016. PMID: 28053825 Free PMC article.

9

Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway.

Haskew-Layton RE, Payappilly JB, Smirnova NA, Ma TC, Chan KK, Murphy TH, Guo H, Langley B, Sultana R, Butterfield DA, Santagata S, Alldred MJ, Gazaryan IG, Bell GW, Ginsberg SD, Ratan RR. Haskew-Layton RE, et al. Among authors: smirnova na. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17385-90. doi: 10.1073/pnas.1003996107. Epub 2010 Sep 20. Proc Natl Acad Sci U S A. 2010. PMID: 20855618 Free PMC article.

10

Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.

Tapias V, Jainuddin S, Ahuja M, Stack C, Elipenahli C, Vignisse J, Gerges M, Starkova N, Xu H, Starkov AA, Bettendorff L, Hushpulian DM, Smirnova NA, Gazaryan IG, Kaidery NA, Wakade S, Calingasan NY, Thomas B, Gibson GE, Dumont M, Beal MF. Tapias V, et al. Among authors: smirnova na. Hum Mol Genet. 2018 Aug 15;27(16):2874-2892. doi: 10.1093/hmg/ddy201. Hum Mol Genet. 2018. PMID: 29860433 Free PMC article.

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