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The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival.
van Spriel AB, de Keijzer S, van der Schaaf A, Gartlan KH, Sofi M, Light A, Linssen PC, Boezeman JB, Zuidscherwoude M, Reinieren-Beeren I, Cambi A, Mackay F, Tarlinton DM, Figdor CG, Wright MD. van Spriel AB, et al. Among authors: light a. Sci Signal. 2012 Nov 13;5(250):ra82. doi: 10.1126/scisignal.2003113. Sci Signal. 2012. PMID: 23150881
The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.
Carotta S, Willis SN, Hasbold J, Inouye M, Pang SH, Emslie D, Light A, Chopin M, Shi W, Wang H, Morse HC 3rd, Tarlinton DM, Corcoran LM, Hodgkin PD, Nutt SL. Carotta S, et al. Among authors: light a. J Exp Med. 2014 Oct 20;211(11):2169-81. doi: 10.1084/jem.20140425. Epub 2014 Oct 6. J Exp Med. 2014. PMID: 25288399 Free PMC article.
Manipulation of B-cell responses with histone deacetylase inhibitors.
Waibel M, Christiansen AJ, Hibbs ML, Shortt J, Jones SA, Simpson I, Light A, O'Donnell K, Morand EF, Tarlinton DM, Johnstone RW, Hawkins ED. Waibel M, et al. Among authors: light a. Nat Commun. 2015 Apr 27;6:6838. doi: 10.1038/ncomms7838. Nat Commun. 2015. PMID: 25913720 Free article.
373 results