Liu D - Search Results

1

mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.

Kim SJ, DeStefano MA, Oh WJ, Wu CC, Vega-Cotto NM, Finlan M, Liu D, Su B, Jacinto E. Kim SJ, et al. Among authors: liu d. Mol Cell. 2012 Dec 28;48(6):875-87. doi: 10.1016/j.molcel.2012.09.029. Epub 2012 Nov 8. Mol Cell. 2012. PMID: 23142081 Free PMC article.

2

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.

Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B. Jacinto E, et al. Among authors: liu d. Cell. 2006 Oct 6;127(1):125-37. doi: 10.1016/j.cell.2006.08.033. Epub 2006 Sep 7. Cell. 2006. PMID: 16962653 Free article.

3

Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells.

Lazorchak AS, Liu D, Facchinetti V, Di Lorenzo A, Sessa WC, Schatz DG, Su B. Lazorchak AS, et al. Among authors: liu d. Mol Cell. 2010 Aug 13;39(3):433-43. doi: 10.1016/j.molcel.2010.07.031. Mol Cell. 2010. PMID: 20705244 Free PMC article.

4

mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif.

Wu YT, Ouyang W, Lazorchak AS, Liu D, Shen HM, Su B. Wu YT, et al. Among authors: liu d. J Biol Chem. 2011 Apr 22;286(16):14190-8. doi: 10.1074/jbc.M111.219923. Epub 2011 Feb 14. J Biol Chem. 2011. PMID: 21321111 Free PMC article.

5

Sin1 regulates Treg-cell development but is not required for T-cell growth and proliferation.

Chang X, Lazorchak AS, Liu D, Su B. Chang X, et al. Among authors: liu d. Eur J Immunol. 2012 Jun;42(6):1639-47. doi: 10.1002/eji.201142066. Eur J Immunol. 2012. PMID: 22678916 Free PMC article.

6

Metabolic regulation of T cell development by Sin1-mTORC2 is mediated by pyruvate kinase M2.

Ouyang X, Han Y, Qu G, Li M, Wu N, Liu H, Arojo O, Sun H, Liu X, Liu D, Chen L, Zou Q, Su B. Ouyang X, et al. Among authors: liu h, liu x, liu d. J Mol Cell Biol. 2019 Feb 1;11(2):93-106. doi: 10.1093/jmcb/mjy065. J Mol Cell Biol. 2019. PMID: 30428057 Free PMC article.

7

Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity.

Al-Tawashi A, Jung SY, Liu D, Su B, Qin J. Al-Tawashi A, et al. Among authors: liu d. J Biol Chem. 2012 Apr 27;287(18):14644-58. doi: 10.1074/jbc.M111.261875. Epub 2012 Feb 28. J Biol Chem. 2012. PMID: 22375002 Free PMC article.

8

Inhibition of the mTORC2 and chaperone pathways to treat leukemia.

Zhang F, Lazorchak AS, Liu D, Chen F, Su B. Zhang F, et al. Among authors: liu d. Blood. 2012 Jun 21;119(25):6080-8. doi: 10.1182/blood-2011-12-399519. Epub 2012 May 7. Blood. 2012. PMID: 22566604 Free article.

9

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.

Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W. Liu P, et al. Among authors: liu d. Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161930 Free PMC article.

10

Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc.

Li M, Lazorchak AS, Ouyang X, Zhang H, Liu H, Arojo OA, Yan L, Jin J, Han Y, Qu G, Fu Y, Xu X, Liu X, Zhang W, Yang Z, Ruan C, Wang Q, Liu D, Huang C, Lu L, Jiang S, Li F, Su B. Li M, et al. Among authors: liu h, liu x, liu d. Cell Mol Immunol. 2019 Sep;16(9):757-769. doi: 10.1038/s41423-018-0185-x. Epub 2019 Jan 31. Cell Mol Immunol. 2019. PMID: 30705387 Free PMC article.

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