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Page 1
Bacteria differentially induce degradation of Bcl-xL, a survival protein, by human platelets.
Kraemer BF, Campbell RA, Schwertz H, Franks ZG, Vieira de Abreu A, Grundler K, Kile BT, Dhakal BK, Rondina MT, Kahr WH, Mulvey MA, Blaylock RC, Zimmerman GA, Weyrich AS. Kraemer BF, et al. Among authors: kahr wh. Blood. 2012 Dec 13;120(25):5014-20. doi: 10.1182/blood-2012-04-420661. Epub 2012 Oct 18. Blood. 2012. PMID: 23086749 Free PMC article.
The Sec1-Munc18 protein VPS33B forms a uniquely bidirectional complex with VPS16B.
Liu RJY, Al-Molieh Y, Chen SZ, Drobac M, Urban D, Chen CH, Yao HHY, Geng RSQ, Li L, Pluthero FG, Benlekbir S, Rubinstein JL, Kahr WHA. Liu RJY, et al. Among authors: kahr wha. J Biol Chem. 2023 Jun;299(6):104718. doi: 10.1016/j.jbc.2023.104718. Epub 2023 Apr 14. J Biol Chem. 2023. PMID: 37062417 Free PMC article.
PACSIN2 regulates platelet integrin β1 hemostatic function.
Biswas R, Boyd EK, Eaton N, Steenackers A, Schulte ML, Reusswig F, Yu H, Drew C, Kahr WHA, Shi Q, Plomann M, Hoffmeister KM, Falet H. Biswas R, et al. Among authors: kahr wha. J Thromb Haemost. 2023 Dec;21(12):3619-3632. doi: 10.1016/j.jtha.2023.08.026. Epub 2023 Sep 9. J Thromb Haemost. 2023. PMID: 37678551
Anucleate platelets generate progeny.
Schwertz H, Köster S, Kahr WH, Michetti N, Kraemer BF, Weitz DA, Blaylock RC, Kraiss LW, Greinacher A, Zimmerman GA, Weyrich AS. Schwertz H, et al. Among authors: kahr wh. Blood. 2010 May 6;115(18):3801-9. doi: 10.1182/blood-2009-08-239558. Epub 2010 Jan 19. Blood. 2010. PMID: 20086251 Free PMC article.
Novel anti-bacterial activities of β-defensin 1 in human platelets: suppression of pathogen growth and signaling of neutrophil extracellular trap formation.
Kraemer BF, Campbell RA, Schwertz H, Cody MJ, Franks Z, Tolley ND, Kahr WH, Lindemann S, Seizer P, Yost CC, Zimmerman GA, Weyrich AS. Kraemer BF, et al. Among authors: kahr wh. PLoS Pathog. 2011 Nov;7(11):e1002355. doi: 10.1371/journal.ppat.1002355. Epub 2011 Nov 10. PLoS Pathog. 2011. PMID: 22102811 Free PMC article.
Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice.
Kahr WH, Lo RW, Li L, Pluthero FG, Christensen H, Ni R, Vaezzadeh N, Hawkins CE, Weyrich AS, Di Paola J, Landolt-Marticorena C, Gross PL. Kahr WH, et al. Blood. 2013 Nov 7;122(19):3349-58. doi: 10.1182/blood-2013-04-499491. Epub 2013 Jul 16. Blood. 2013. PMID: 23861251 Free PMC article.
Proteasome function is required for platelet production.
Shi DS, Smith MC, Campbell RA, Zimmerman PW, Franks ZB, Kraemer BF, Machlus KR, Ling J, Kamba P, Schwertz H, Rowley JW, Miles RR, Liu ZJ, Sola-Visner M, Italiano JE Jr, Christensen H, Kahr WH, Li DY, Weyrich AS. Shi DS, et al. Among authors: kahr wh. J Clin Invest. 2014 Sep;124(9):3757-66. doi: 10.1172/JCI75247. Epub 2014 Jul 25. J Clin Invest. 2014. PMID: 25061876 Free PMC article.
Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia.
Noetzli L, Lo RW, Lee-Sherick AB, Callaghan M, Noris P, Savoia A, Rajpurkar M, Jones K, Gowan K, Balduini C, Pecci A, Gnan C, De Rocco D, Doubek M, Li L, Lu L, Leung R, Landolt-Marticorena C, Hunger S, Heller P, Gutierrez-Hartmann A, Xiayuan L, Pluthero FG, Rowley JW, Weyrich AS, Kahr WHA, Porter CC, Di Paola J. Noetzli L, et al. Nat Genet. 2015 May;47(5):535-538. doi: 10.1038/ng.3253. Epub 2015 Mar 25. Nat Genet. 2015. PMID: 25807284 Free PMC article.
103 results