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Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 β-cell survival.
Biochim Biophys Acta. 2013 Feb;1831(2):251-62. doi: 10.1016/j.bbalip.2012.10.003. Epub 2012 Oct 17.
Biochim Biophys Acta. 2013.
PMID: 23085009
Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells.
Véret J, Coant N, Berdyshev EV, Skobeleva A, Therville N, Bailbé D, Gorshkova I, Natarajan V, Portha B, Le Stunff H.
Véret J, et al. Among authors: skobeleva a.
Biochem J. 2011 Aug 15;438(1):177-89. doi: 10.1042/BJ20101386.
Biochem J. 2011.
PMID: 21592087
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FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells.
Berdyshev EV, Gorshkova I, Skobeleva A, Bittman R, Lu X, Dudek SM, Mirzapoiazova T, Garcia JG, Natarajan V.
Berdyshev EV, et al. Among authors: skobeleva a.
J Biol Chem. 2009 Feb 27;284(9):5467-77. doi: 10.1074/jbc.M805186200. Epub 2009 Jan 1.
J Biol Chem. 2009.
PMID: 19119142
Free PMC article.
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Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema.
Diab KJ, Adamowicz JJ, Kamocki K, Rush NI, Garrison J, Gu Y, Schweitzer KS, Skobeleva A, Rajashekhar G, Hubbard WC, Berdyshev EV, Petrache I.
Diab KJ, et al. Among authors: skobeleva a.
Am J Respir Crit Care Med. 2010 Feb 15;181(4):344-52. doi: 10.1164/rccm.200906-0826OC. Epub 2009 Dec 3.
Am J Respir Crit Care Med. 2010.
PMID: 19965812
Free PMC article.
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Sphingosine kinase localization in the control of sphingolipid metabolism.
Siow DL, Anderson CD, Berdyshev EV, Skobeleva A, Natarajan V, Pitson SM, Wattenberg BW.
Siow DL, et al. Among authors: skobeleva a.
Adv Enzyme Regul. 2011;51(1):229-44. doi: 10.1016/j.advenzreg.2010.09.004. Epub 2010 Nov 12.
Adv Enzyme Regul. 2011.
PMID: 21075134
Free PMC article.
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Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate.
Siow DL, Anderson CD, Berdyshev EV, Skobeleva A, Pitson SM, Wattenberg BW.
Siow DL, et al. Among authors: skobeleva a.
J Lipid Res. 2010 Sep;51(9):2546-59. doi: 10.1194/jlr.M004374. Epub 2010 Apr 12.
J Lipid Res. 2010.
PMID: 20386061
Free PMC article.
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Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivo.
Tomsig JL, Snyder AH, Berdyshev EV, Skobeleva A, Mataya C, Natarajan V, Brindley DN, Lynch KR.
Tomsig JL, et al. Among authors: skobeleva a.
Biochem J. 2009 May 1;419(3):611-8. doi: 10.1042/BJ20081888.
Biochem J. 2009.
PMID: 19215222
Free PMC article.
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Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells.
Mesicek J, Lee H, Feldman T, Jiang X, Skobeleva A, Berdyshev EV, Haimovitz-Friedman A, Fuks Z, Kolesnick R.
Mesicek J, et al. Among authors: skobeleva a.
Cell Signal. 2010 Sep;22(9):1300-7. doi: 10.1016/j.cellsig.2010.04.006. Epub 2010 Apr 18.
Cell Signal. 2010.
PMID: 20406683
Free PMC article.
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