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Genetic ablation of soluble tumor necrosis factor with preservation of membrane tumor necrosis factor is associated with neuroprotection after focal cerebral ischemia.
Madsen PM, Clausen BH, Degn M, Thyssen S, Kristensen LK, Svensson M, Ditzel N, Finsen B, Deierborg T, Brambilla R, Lambertsen KL. Madsen PM, et al. Among authors: lambertsen kl. J Cereb Blood Flow Metab. 2016 Sep;36(9):1553-69. doi: 10.1177/0271678X15610339. Epub 2015 Oct 19. J Cereb Blood Flow Metab. 2016. PMID: 26661199 Free PMC article.
Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.
Bøttger P, Glerup S, Gesslein B, Illarionova NB, Isaksen TJ, Heuck A, Clausen BH, Füchtbauer EM, Gramsbergen JB, Gunnarson E, Aperia A, Lauritzen M, Lambertsen KL, Nissen P, Lykke-Hartmann K. Bøttger P, et al. Among authors: lambertsen kl. Sci Rep. 2016 Feb 25;6:22047. doi: 10.1038/srep22047. Sci Rep. 2016. PMID: 26911348 Free PMC article.
Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling.
Clausen BH, Degn M, Sivasaravanaparan M, Fogtmann T, Andersen MG, Trojanowsky MD, Gao H, Hvidsten S, Baun C, Deierborg T, Finsen B, Kristensen BW, Bak ST, Meyer M, Lee J, Nedospasov SA, Brambilla R, Lambertsen KL. Clausen BH, et al. Among authors: lambertsen kl. Sci Rep. 2016 Jul 7;6:29291. doi: 10.1038/srep29291. Sci Rep. 2016. PMID: 27384243 Free PMC article.
Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine.
Severino M, Sivasaravanaparan M, Olesen LØ, von Linstow CU, Metaxas A, Bouzinova EV, Khan AM, Lambertsen KL, Babcock AA, Gramsbergen JB, Wiborg O, Finsen B. Severino M, et al. Among authors: lambertsen kl. Alzheimers Dement (N Y). 2018 May 24;4:215-223. doi: 10.1016/j.trci.2018.04.005. eCollection 2018. Alzheimers Dement (N Y). 2018. PMID: 29955664 Free PMC article.
TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex.
Yli-Karjanmaa M, Larsen KS, Fenger CD, Kristensen LK, Martin NA, Jensen PT, Breton A, Nathanson L, Nielsen PV, Lund MC, Carlsen SL, Gramsbergen JB, Finsen B, Stubbe J, Frich LH, Stolp H, Brambilla R, Anthony DC, Meyer M, Lambertsen KL. Yli-Karjanmaa M, et al. Among authors: lambertsen kl. Brain Behav Immun. 2019 Nov;82:279-297. doi: 10.1016/j.bbi.2019.08.195. Epub 2019 Sep 7. Brain Behav Immun. 2019. PMID: 31505254 Free article.
Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia.
Clausen BH, Degn M, Martin NA, Couch Y, Karimi L, Ormhøj M, Mortensen ML, Gredal HB, Gardiner C, Sargent II, Szymkowski DE, Petit GH, Deierborg T, Finsen B, Anthony DC, Lambertsen KL. Clausen BH, et al. Among authors: lambertsen kl. J Neuroinflammation. 2014 Dec 12;11:203. doi: 10.1186/s12974-014-0203-6. J Neuroinflammation. 2014. PMID: 25498129 Free PMC article.
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