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Experimental and in silico modelling analyses of the gene expression pathway for recombinant antibody and by-product production in NS0 cell lines.
PLoS One. 2012;7(10):e47422. doi: 10.1371/journal.pone.0047422. Epub 2012 Oct 10.
PLoS One. 2012.
PMID: 23071804
Free PMC article.
Identification of the limitations on recombinant gene expression in CHO cell lines with varying luciferase production rates.
Mead EJ, Chiverton LM, Smales CM, von der Haar T.
Mead EJ, et al. Among authors: chiverton lm.
Biotechnol Bioeng. 2009 Apr 15;102(6):1593-602. doi: 10.1002/bit.22201.
Biotechnol Bioeng. 2009.
PMID: 19090535
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Quantitative definition and monitoring of the host cell protein proteome using iTRAQ - a study of an industrial mAb producing CHO-S cell line.
Chiverton LM, Evans C, Pandhal J, Landels AR, Rees BJ, Levison PR, Wright PC, Smales CM.
Chiverton LM, et al.
Biotechnol J. 2016 Aug;11(8):1014-24. doi: 10.1002/biot.201500550. Epub 2016 Jun 22.
Biotechnol J. 2016.
PMID: 27214759
Free PMC article.
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Characterization of Host Cell Proteins (HCPs) in CHO Cell Bioprocesses.
Hogwood CEM, Chiverton LM, Mark Smales C.
Hogwood CEM, et al. Among authors: chiverton lm.
Methods Mol Biol. 2017;1603:243-250. doi: 10.1007/978-1-4939-6972-2_16.
Methods Mol Biol. 2017.
PMID: 28493135
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Modern challenges in therapeutic protein production.
Chiverton LM.
Chiverton LM.
Expert Rev Proteomics. 2010 Oct;7(5):635-7. doi: 10.1586/epr.10.86.
Expert Rev Proteomics. 2010.
PMID: 20973635
Review.
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Conference scene: miniaturisation - micro scale bioprocess development.
Chiverton LM.
Chiverton LM.
Immunotherapy. 2011 Jan;3(1):13-6. doi: 10.2217/imt.10.97.
Immunotherapy. 2011.
PMID: 21174552
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