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Physical interaction between neurofibromin and serotonin 5-HT6 receptor promotes receptor constitutive activity.
Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12310-12315. doi: 10.1073/pnas.1600914113. Epub 2016 Oct 10.
Proc Natl Acad Sci U S A. 2016.
PMID: 27791021
Free PMC article.
Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling.
Cobret L, De Tauzia ML, Ferent J, Traiffort E, Hénaoui I, Godin F, Kellenberger E, Rognan D, Pantel J, Bénédetti H, Morisset-Lopez S.
Cobret L, et al. Among authors: de tauzia ml.
Br J Pharmacol. 2015 Feb;172(3):841-56. doi: 10.1111/bph.12945. Epub 2014 Dec 15.
Br J Pharmacol. 2015.
PMID: 25257685
Free PMC article.
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New in-capillary electrophoretic kinase assays to evaluate inhibitors of the PI3k/Akt/mTOR signaling pathway.
Nehmé R, Nehmé H, Saurat T, de-Tauzia ML, Buron F, Lafite P, Verrelle P, Chautard E, Morin P, Routier S, Bénédetti H.
Nehmé R, et al. Among authors: de tauzia ml.
Anal Bioanal Chem. 2014 Jun;406(15):3743-54. doi: 10.1007/s00216-014-7790-z. Epub 2014 May 11.
Anal Bioanal Chem. 2014.
PMID: 24817345
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Design, synthesis, and biological activity of pyridopyrimidine scaffolds as novel PI3K/mTOR dual inhibitors.
Saurat T, Buron F, Rodrigues N, de Tauzia ML, Colliandre L, Bourg S, Bonnet P, Guillaumet G, Akssira M, Corlu A, Guillouzo C, Berthier P, Rio P, Jourdan ML, Bénédetti H, Routier S.
Saurat T, et al. Among authors: de tauzia ml.
J Med Chem. 2014 Feb 13;57(3):613-31. doi: 10.1021/jm401138v. Epub 2014 Jan 21.
J Med Chem. 2014.
PMID: 24345273
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Nf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathways.
Vallée B, Doudeau M, Godin F, Gombault A, Tchalikian A, de Tauzia ML, Bénédetti H.
Vallée B, et al. Among authors: de tauzia ml.
PLoS One. 2012;7(10):e47283. doi: 10.1371/journal.pone.0047283. Epub 2012 Oct 17.
PLoS One. 2012.
PMID: 23082153
Free PMC article.
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Synthesis and biological evaluation of new 5-benzylated 4-oxo-3,4-dihydro-5H-pyridazino[4,5-b]indoles as PI3Kα inhibitors.
Bruel A, Logé C, Tauzia ML, Ravache M, Le Guevel R, Guillouzo C, Lohier JF, Oliveira Santos JS, Lozach O, Meijer L, Ruchaud S, Bénédetti H, Robert JM.
Bruel A, et al. Among authors: tauzia ml.
Eur J Med Chem. 2012 Nov;57:225-33. doi: 10.1016/j.ejmech.2012.09.001. Epub 2012 Sep 10.
Eur J Med Chem. 2012.
PMID: 23063566
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