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Black mamba venom peptides target acid-sensing ion channels to abolish pain.
Diochot S, Baron A, Salinas M, Douguet D, Scarzello S, Dabert-Gay AS, Debayle D, Friend V, Alloui A, Lazdunski M, Lingueglia E. Diochot S, et al. Among authors: baron a. Nature. 2012 Oct 25;490(7421):552-5. doi: 10.1038/nature11494. Epub 2012 Oct 3. Nature. 2012. PMID: 23034652 Free article.
Zn2+ and H+ are coactivators of acid-sensing ion channels.
Baron A, Schaefer L, Lingueglia E, Champigny G, Lazdunski M. Baron A, et al. J Biol Chem. 2001 Sep 21;276(38):35361-7. doi: 10.1074/jbc.M105208200. Epub 2001 Jul 16. J Biol Chem. 2001. PMID: 11457851 Free article.
1,130 results