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Synthesis of indolylquinolines, indolylacridines, and indolylcyclopenta[b]quinolines from the Baylis-Hillman adducts: an in situ [1,3]-sigmatropic rearrangement of an indole nucleus to access indolylacridines and indolylcyclopenta[b]quinolines.
J Org Chem. 2012 Oct 5;77(19):8451-64. doi: 10.1021/jo301313m. Epub 2012 Sep 25.
J Org Chem. 2012.
PMID: 22967265
Synthesis of isocoumarin derivatives via the copper-catalyzed tandem sequential cyclization of 2-halo-N-phenyl benzamides and acyclic 1,3-diketones.
Kavala V, Wang CC, Barange DK, Kuo CW, Lei PM, Yao CF.
Kavala V, et al. Among authors: lei pm.
J Org Chem. 2012 Jun 1;77(11):5022-9. doi: 10.1021/jo300501j. Epub 2012 May 21.
J Org Chem. 2012.
PMID: 22512674
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A convenient one-pot preparation of 2-methyl-3-(phenylthio- methyl)quinolines from Morita-Baylis-Hillman adducts and their oxidation to the corresponding sulfones.
Ramesh C, Lei PM, Kavala V, Kuo CW, Yao CF.
Ramesh C, et al. Among authors: lei pm.
Molecules. 2012 May 3;17(5):5081-94. doi: 10.3390/molecules17055081.
Molecules. 2012.
PMID: 22555297
Free PMC article.
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A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy.
Yang GJ, Wang W, Lei PM, Leung CH, Ma DL.
Yang GJ, et al. Among authors: lei pm.
Int J Biol Macromol. 2020 Dec 1;164:3204-3220. doi: 10.1016/j.ijbiomac.2020.08.194. Epub 2020 Aug 26.
Int J Biol Macromol. 2020.
PMID: 32860796
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Mimicking Strategy for Protein-Protein Interaction Inhibitor Discovery by Virtual Screening.
Wu KJ, Lei PM, Liu H, Wu C, Leung CH, Ma DL.
Wu KJ, et al. Among authors: lei pm.
Molecules. 2019 Dec 4;24(24):4428. doi: 10.3390/molecules24244428.
Molecules. 2019.
PMID: 31817099
Free PMC article.
Review.
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Pharmacological Inhibition of LSD1 for Cancer Treatment.
Yang GJ, Lei PM, Wong SY, Ma DL, Leung CH.
Yang GJ, et al. Among authors: lei pm.
Molecules. 2018 Dec 4;23(12):3194. doi: 10.3390/molecules23123194.
Molecules. 2018.
PMID: 30518104
Free PMC article.
Review.
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