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Synthesis of indolylquinolines, indolylacridines, and indolylcyclopenta[b]quinolines from the Baylis-Hillman adducts: an in situ [1,3]-sigmatropic rearrangement of an indole nucleus to access indolylacridines and indolylcyclopenta[b]quinolines.
J Org Chem. 2012 Oct 5;77(19):8451-64. doi: 10.1021/jo301313m. Epub 2012 Sep 25.
J Org Chem. 2012.
PMID: 22967265
Alcohol mediated synthesis of 4-oxo-2-aryl-4H-chromene-3-carboxylate derivatives from 4-hydroxycoumarins.
Zanwar MR, Raihan MJ, Gawande SD, Kavala V, Janreddy D, Kuo CW, Ambre R, Yao CF.
Zanwar MR, et al. Among authors: janreddy d.
J Org Chem. 2012 Aug 3;77(15):6495-504. doi: 10.1021/jo301044y. Epub 2012 Jul 24.
J Org Chem. 2012.
PMID: 22809001
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Molecular iodine-mediated reaction of 2-(2-phenylethynyl)-Morita-Baylis-Hillman adducts: an easy route to naphthyl ketones and iodo-substituted isochromenes.
Janreddy D, Kavala V, Kotipalli T, Rajawinslin RR, Kuo CW, Huang WC, Yao CF.
Janreddy D, et al.
Org Biomol Chem. 2014 Nov 7;12(41):8247-56. doi: 10.1039/c4ob00938j. Epub 2014 Sep 9.
Org Biomol Chem. 2014.
PMID: 25203199
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Indole and synthetic derivative activate chaperone expression to reduce polyQ aggregation in SCA17 neuronal cell and slice culture models.
Kung PJ, Tao YC, Hsu HC, Chen WL, Lin TH, Janreddy D, Yao CF, Chang KH, Lin JY, Su MT, Wu CH, Lee-Chen GJ, Hsieh-Li HM.
Kung PJ, et al. Among authors: janreddy d.
Drug Des Devel Ther. 2014 Oct 16;8:1929-39. doi: 10.2147/DDDT.S67376. eCollection 2014.
Drug Des Devel Ther. 2014.
PMID: 25342886
Free PMC article.
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The potential of indole and a synthetic derivative for polyQ aggregation reduction by enhancement of the chaperone and autophagy systems.
Lin CH, Wu YR, Kung PJ, Chen WL, Lee LC, Lin TH, Chao CY, Chen CM, Chang KH, Janreddy D, Lee-Chen GJ, Yao CF.
Lin CH, et al. Among authors: janreddy d.
ACS Chem Neurosci. 2014 Oct 15;5(10):1063-74. doi: 10.1021/cn500075u. Epub 2014 Sep 19.
ACS Chem Neurosci. 2014.
PMID: 25197952
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