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Anorexia/cachexia of chronic diseases: a role for the TGF-β family cytokine MIC-1/GDF15.
Tsai VW, Husaini Y, Manandhar R, Lee-Ng KK, Zhang HP, Harriott K, Jiang L, Lin S, Sainsbury A, Brown DA, Breit SN. Tsai VW, et al. Among authors: breit sn. J Cachexia Sarcopenia Muscle. 2012 Dec;3(4):239-43. doi: 10.1007/s13539-012-0082-6. Epub 2012 Aug 31. J Cachexia Sarcopenia Muscle. 2012. PMID: 22936174 Free PMC article.
MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily.
Bootcov MR, Bauskin AR, Valenzuela SM, Moore AG, Bansal M, He XY, Zhang HP, Donnellan M, Mahler S, Pryor K, Walsh BJ, Nicholson RC, Fairlie WD, Por SB, Robbins JM, Breit SN. Bootcov MR, et al. Among authors: breit sn. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11514-9. doi: 10.1073/pnas.94.21.11514. Proc Natl Acad Sci U S A. 1997. PMID: 9326641 Free PMC article.
The propeptide of the transforming growth factor-beta superfamily member, macrophage inhibitory cytokine-1 (MIC-1), is a multifunctional domain that can facilitate protein folding and secretion.
Fairlie WD, Zhang HP, Wu WM, Pankhurst SL, Bauskin AR, Russell PK, Brown PK, Breit SN. Fairlie WD, et al. Among authors: breit sn. J Biol Chem. 2001 May 18;276(20):16911-8. doi: 10.1074/jbc.M010000200. Epub 2001 Feb 26. J Biol Chem. 2001. PMID: 11278594 Free article.
167 results