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Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.
White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, Houghton R, Estabel J, Bottomley JR, Melvin DG, Sunter D, Adams NC; Sanger Institute Mouse Genetics Project; Tannahill D, Logan DW, Macarthur DG, Flint J, Mahajan VB, Tsang SH, Smyth I, Watt FM, Skarnes WC, Dougan G, Adams DJ, Ramirez-Solis R, Bradley A, Steel KP. White JK, et al. Among authors: logan dw. Cell. 2013 Jul 18;154(2):452-64. doi: 10.1016/j.cell.2013.06.022. Cell. 2013. PMID: 23870131 Free PMC article.
BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription.
Dias C, Estruch SB, Graham SA, McRae J, Sawiak SJ, Hurst JA, Joss SK, Holder SE, Morton JE, Turner C, Thevenon J, Mellul K, Sánchez-Andrade G, Ibarra-Soria X, Deriziotis P, Santos RF, Lee SC, Faivre L, Kleefstra T, Liu P, Hurles ME; DDD Study; Fisher SE, Logan DW. Dias C, et al. Among authors: logan dw. Am J Hum Genet. 2016 Aug 4;99(2):253-74. doi: 10.1016/j.ajhg.2016.05.030. Epub 2016 Jul 21. Am J Hum Genet. 2016. PMID: 27453576 Free PMC article.
Generation of the Sotos syndrome deletion in mice.
Migdalska AM, van der Weyden L, Ismail O; Sanger Mouse Genetics Project; Rust AG, Rashid M, White JK, Sánchez-Andrade G, Lupski JR, Logan DW, Arends MJ, Adams DJ. Migdalska AM, et al. Among authors: logan dw. Mamm Genome. 2012 Dec;23(11-12):749-57. doi: 10.1007/s00335-012-9416-0. Epub 2012 Aug 29. Mamm Genome. 2012. PMID: 22926222 Free PMC article.
Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.
McIntyre RE, Lakshminarasimhan Chavali P, Ismail O, Carragher DM, Sanchez-Andrade G, Forment JV, Fu B, Del Castillo Velasco-Herrera M, Edwards A, van der Weyden L, Yang F; Sanger Mouse Genetics Project; Ramirez-Solis R, Estabel J, Gallagher FA, Logan DW, Arends MJ, Tsang SH, Mahajan VB, Scudamore CL, White JK, Jackson SP, Gergely F, Adams DJ. McIntyre RE, et al. Among authors: logan dw. PLoS Genet. 2012;8(11):e1003022. doi: 10.1371/journal.pgen.1003022. Epub 2012 Nov 15. PLoS Genet. 2012. PMID: 23166506 Free PMC article.
71 results