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Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells.
Yogev N, Frommer F, Lukas D, Kautz-Neu K, Karram K, Ielo D, von Stebut E, Probst HC, van den Broek M, Riethmacher D, Birnberg T, Blank T, Reizis B, Korn T, Wiendl H, Jung S, Prinz M, Kurschus FC, Waisman A. Yogev N, et al. Among authors: jung s. Immunity. 2012 Aug 24;37(2):264-75. doi: 10.1016/j.immuni.2012.05.025. Epub 2012 Aug 16. Immunity. 2012. PMID: 22902234 Free article.
Tumor necrosis factor alpha- and inducible nitric oxide synthase-producing dendritic cells are rapidly recruited to the bladder in urinary tract infection but are dispensable for bacterial clearance.
Engel D, Dobrindt U, Tittel A, Peters P, Maurer J, Gütgemann I, Kaissling B, Kuziel W, Jung S, Kurts C. Engel D, et al. Among authors: jung s. Infect Immun. 2006 Nov;74(11):6100-7. doi: 10.1128/IAI.00881-06. Epub 2006 Sep 11. Infect Immun. 2006. PMID: 16966414 Free PMC article.
Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome.
Birnberg T, Bar-On L, Sapoznikov A, Caton ML, Cervantes-Barragán L, Makia D, Krauthgamer R, Brenner O, Ludewig B, Brockschnieder D, Riethmacher D, Reizis B, Jung S. Birnberg T, et al. Among authors: jung s. Immunity. 2008 Dec 19;29(6):986-97. doi: 10.1016/j.immuni.2008.10.012. Epub 2008 Dec 8. Immunity. 2008. PMID: 19062318 Free article.
CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice.
Weber C, Meiler S, Döring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Förster I, Zenke M, Hieronymus T, Junt T, Zernecke A. Weber C, et al. Among authors: jung s. J Clin Invest. 2011 Jul;121(7):2898-910. doi: 10.1172/JCI44925. J Clin Invest. 2011. PMID: 21633167 Free PMC article.
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