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Novel oxysterols activate the Hedgehog pathway and induce osteogenesis.
Bioorg Med Chem Lett. 2012 Sep 15;22(18):5893-7. doi: 10.1016/j.bmcl.2012.07.073. Epub 2012 Jul 27.
Bioorg Med Chem Lett. 2012.
PMID: 22901899
Novel oxysterols have pro-osteogenic and anti-adipogenic effects in vitro and induce spinal fusion in vivo.
Johnson JS, Meliton V, Kim WK, Lee KB, Wang JC, Nguyen K, Yoo D, Jung ME, Atti E, Tetradis S, Pereira RC, Magyar C, Nargizyan T, Hahn TJ, Farouz F, Thies S, Parhami F.
Johnson JS, et al. Among authors: farouz f.
J Cell Biochem. 2011 Jun;112(6):1673-84. doi: 10.1002/jcb.23082.
J Cell Biochem. 2011.
PMID: 21503957
Free PMC article.
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Discovery of a potent, orally bioavailable pyrimidine VLA-4 antagonist effective in a sheep asthma model.
Semko CM, Chen L, Dressen DB, Dreyer ML, Dunn W, Farouz FS, Freedman SB, Holsztynska EJ, Jefferies M, Konradi AW, Liao A, Lugar J, Mutter L, Pleiss MA, Quinn KP, Thompson T, Thorsett ED, Vandevert C, Xu YZ, Yednock TA.
Semko CM, et al. Among authors: farouz fs.
Bioorg Med Chem Lett. 2011 Mar 15;21(6):1741-3. doi: 10.1016/j.bmcl.2011.01.075. Epub 2011 Jan 22.
Bioorg Med Chem Lett. 2011.
PMID: 21316228
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