Kvaratskhelia M - Search Results

1

Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2).

Larue R, Gupta K, Wuensch C, Shkriabai N, Kessl JJ, Danhart E, Feng L, Taltynov O, Christ F, Van Duyne GD, Debyser Z, Foster MP, Kvaratskhelia M. Larue R, et al. Among authors: kvaratskhelia m. J Biol Chem. 2012 Oct 5;287(41):34044-58. doi: 10.1074/jbc.M112.384669. Epub 2012 Aug 7. J Biol Chem. 2012. PMID: 22872640 Free PMC article.

2

The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function.

Singer MR, Dinh T, Levintov L, Annamalai AS, Rey JS, Briganti L, Cook NJ, Pye VE, Taylor IA, Kim K, Engelman AN, Kim B, Perilla JR, Kvaratskhelia M, Cherepanov P. Singer MR, et al. Among authors: kvaratskhelia m. mBio. 2023 Feb 28;14(1):e0356022. doi: 10.1128/mbio.03560-22. Epub 2023 Feb 6. mBio. 2023. PMID: 36744954 Free PMC article.

3

Identification of an inhibitor-binding site to HIV-1 integrase with affinity acetylation and mass spectrometry.

Shkriabai N, Patil SS, Hess S, Budihas SR, Craigie R, Burke TR Jr, Le Grice SF, Kvaratskhelia M. Shkriabai N, et al. Among authors: kvaratskhelia m. Proc Natl Acad Sci U S A. 2004 May 4;101(18):6894-9. doi: 10.1073/pnas.0400873101. Epub 2004 Apr 26. Proc Natl Acad Sci U S A. 2004. PMID: 15118107 Free PMC article.

4

Mass spectrometric analysis of the HIV-1 integrase-pyridoxal 5'-phosphate complex reveals a new binding site for a nucleotide inhibitor.

Williams KL, Zhang Y, Shkriabai N, Karki RG, Nicklaus MC, Kotrikadze N, Hess S, Le Grice SF, Craigie R, Pathak VK, Kvaratskhelia M. Williams KL, et al. Among authors: kvaratskhelia m. J Biol Chem. 2005 Mar 4;280(9):7949-55. doi: 10.1074/jbc.M413579200. Epub 2004 Dec 22. J Biol Chem. 2005. PMID: 15615720 Free article.

5

Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding.

Zhao Z, McKee CJ, Kessl JJ, Santos WL, Daigle JE, Engelman A, Verdine G, Kvaratskhelia M. Zhao Z, et al. Among authors: kvaratskhelia m. J Biol Chem. 2008 Feb 29;283(9):5632-41. doi: 10.1074/jbc.M705241200. Epub 2007 Dec 19. J Biol Chem. 2008. PMID: 18093980 Free PMC article.

6

Dynamic modulation of HIV-1 integrase structure and function by cellular lens epithelium-derived growth factor (LEDGF) protein.

McKee CJ, Kessl JJ, Shkriabai N, Dar MJ, Engelman A, Kvaratskhelia M. McKee CJ, et al. Among authors: kvaratskhelia m. J Biol Chem. 2008 Nov 14;283(46):31802-12. doi: 10.1074/jbc.M805843200. Epub 2008 Sep 18. J Biol Chem. 2008. PMID: 18801737 Free PMC article.

7

Mass spectrometry-based footprinting of protein-protein interactions.

McKee CJ, Kessl JJ, Norris JO, Shkriabai N, Kvaratskhelia M. McKee CJ, et al. Among authors: kvaratskhelia m. Methods. 2009 Apr;47(4):304-7. doi: 10.1016/j.ymeth.2008.10.023. Epub 2008 Nov 17. Methods. 2009. PMID: 19015031 Free PMC article.

8

Checkpoint kinase ATR promotes nucleotide excision repair of UV-induced DNA damage via physical interaction with xeroderma pigmentosum group A.

Shell SM, Li Z, Shkriabai N, Kvaratskhelia M, Brosey C, Serrano MA, Chazin WJ, Musich PR, Zou Y. Shell SM, et al. Among authors: kvaratskhelia m. J Biol Chem. 2009 Sep 4;284(36):24213-22. doi: 10.1074/jbc.M109.000745. Epub 2009 Jul 8. J Biol Chem. 2009. PMID: 19586908 Free PMC article.

9

An allosteric mechanism for inhibiting HIV-1 integrase with a small molecule.

Kessl JJ, Eidahl JO, Shkriabai N, Zhao Z, McKee CJ, Hess S, Burke TR Jr, Kvaratskhelia M. Kessl JJ, et al. Among authors: kvaratskhelia m. Mol Pharmacol. 2009 Oct;76(4):824-32. doi: 10.1124/mol.109.058883. Epub 2009 Jul 28. Mol Pharmacol. 2009. PMID: 19638533 Free PMC article.

10

Identification of host proteins associated with HIV-1 preintegration complexes isolated from infected CD4+ cells.

Raghavendra NK, Shkriabai N, Graham RLj, Hess S, Kvaratskhelia M, Wu L. Raghavendra NK, et al. Among authors: kvaratskhelia m. Retrovirology. 2010 Aug 11;7:66. doi: 10.1186/1742-4690-7-66. Retrovirology. 2010. PMID: 20698996 Free PMC article.

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