Hughes DA - Search Results

1

Human quercetin conjugated metabolites attenuate TNF-α-induced changes in vasomodulatory molecules in an HUASMCs/HUVECs co-culture model.

Lodi F, Winterbone MS, Tribolo S, Needs PW, Hughes DA, Kroon PA. Lodi F, et al. Among authors: hughes da. Planta Med. 2012 Sep;78(14):1571-3. doi: 10.1055/s-0032-1315148. Epub 2012 Aug 3. Planta Med. 2012. PMID: 22864987

2

Physiologically relevant metabolites of quercetin have no effect on adhesion molecule or chemokine expression in human vascular smooth muscle cells.

Winterbone MS, Tribolo S, Needs PW, Kroon PA, Hughes DA. Winterbone MS, et al. Among authors: hughes da. Atherosclerosis. 2009 Feb;202(2):431-8. doi: 10.1016/j.atherosclerosis.2008.04.040. Epub 2008 May 1. Atherosclerosis. 2009. PMID: 18489909

3

Human metabolic transformation of quercetin blocks its capacity to decrease endothelial nitric oxide synthase (eNOS) expression and endothelin-1 secretion by human endothelial cells.

Tribolo S, Lodi F, Winterbone MS, Saha S, Needs PW, Hughes DA, Kroon PA. Tribolo S, et al. Among authors: hughes da. J Agric Food Chem. 2013 Sep 11;61(36):8589-96. doi: 10.1021/jf402511c. Epub 2013 Aug 28. J Agric Food Chem. 2013. PMID: 23947593

4

Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells.

Tribolo S, Lodi F, Connor C, Suri S, Wilson VG, Taylor MA, Needs PW, Kroon PA, Hughes DA. Tribolo S, et al. Among authors: hughes da. Atherosclerosis. 2008 Mar;197(1):50-6. doi: 10.1016/j.atherosclerosis.2007.07.040. Epub 2007 Sep 18. Atherosclerosis. 2008. PMID: 17880982

5

Quercetin and its major metabolites selectively modulate cyclic GMP-dependent relaxations and associated tolerance in pig isolated coronary artery.

Suri S, Liu XH, Rayment S, Hughes DA, Kroon PA, Needs PW, Taylor MA, Tribolo S, Wilson VG. Suri S, et al. Among authors: hughes da. Br J Pharmacol. 2010 Feb 1;159(3):566-75. doi: 10.1111/j.1476-5381.2009.00556.x. Epub 2009 Dec 24. Br J Pharmacol. 2010. PMID: 20050852 Free PMC article.

6

A comparative study of the effects of quercetin and its glucuronide and sulfate metabolites on human neutrophil function in vitro.

Suri S, Taylor MA, Verity A, Tribolo S, Needs PW, Kroon PA, Hughes DA, Wilson VG. Suri S, et al. Among authors: hughes da. Biochem Pharmacol. 2008 Sep 1;76(5):645-53. doi: 10.1016/j.bcp.2008.06.010. Epub 2008 Jul 1. Biochem Pharmacol. 2008. PMID: 18639531

7

Quercetin and its principal metabolites, but not myricetin, oppose lipopolysaccharide-induced hyporesponsiveness of the porcine isolated coronary artery.

Al-Shalmani S, Suri S, Hughes DA, Kroon PA, Needs PW, Taylor MA, Tribolo S, Wilson VG. Al-Shalmani S, et al. Among authors: hughes da. Br J Pharmacol. 2011 Apr;162(7):1485-97. doi: 10.1111/j.1476-5381.2010.00919.x. Br J Pharmacol. 2011. PMID: 21375526 Free PMC article.

8

Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.

Lodi F, Jimenez R, Moreno L, Kroon PA, Needs PW, Hughes DA, Santos-Buelga C, Gonzalez-Paramas A, Cogolludo A, Lopez-Sepulveda R, Duarte J, Perez-Vizcaino F. Lodi F, et al. Among authors: hughes da. Atherosclerosis. 2009 May;204(1):34-9. doi: 10.1016/j.atherosclerosis.2008.08.007. Epub 2008 Aug 14. Atherosclerosis. 2009. PMID: 18801486

9

Pro-oxidant effect of alpha-tocopherol in patients with type 2 diabetes after an oral glucose tolerance test--a randomised controlled trial.

Winterbone MS, Sampson MJ, Saha S, Hughes JC, Hughes DA. Winterbone MS, et al. Among authors: hughes da, hughes jc. Cardiovasc Diabetol. 2007 Feb 22;6:8. doi: 10.1186/1475-2840-6-8. Cardiovasc Diabetol. 2007. PMID: 17316429 Free PMC article. Clinical Trial.

10

Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes.

Sampson MJ, Winterbone MS, Hughes JC, Dozio N, Hughes DA. Sampson MJ, et al. Among authors: hughes da, hughes jc. Diabetes Care. 2006 Feb;29(2):283-9. doi: 10.2337/diacare.29.02.06.dc05-1715. Diabetes Care. 2006. PMID: 16443874

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