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Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog.
Bourgonje VJ, Schoenmakers M, Beekman JD, van der Nagel R, Houtman MJ, Miedema LF, Antoons G, Sipido K, de Windt LJ, van Veen TA, Vos MA. Bourgonje VJ, et al. Among authors: de windt lj. Heart Rhythm. 2012 Nov;9(11):1875-83. doi: 10.1016/j.hrthm.2012.07.023. Epub 2012 Jul 27. Heart Rhythm. 2012. PMID: 22846339
Downregulation of apoptosis-inducing factor in harlequin mutant mice sensitizes the myocardium to oxidative stress-related cell death and pressure overload-induced decompensation.
van Empel VP, Bertrand AT, van der Nagel R, Kostin S, Doevendans PA, Crijns HJ, de Wit E, Sluiter W, Ackerman SL, De Windt LJ. van Empel VP, et al. Among authors: de windt lj, de wit e. Circ Res. 2005 Jun 24;96(12):e92-e101. doi: 10.1161/01.RES.0000172081.30327.28. Epub 2005 Jun 2. Circ Res. 2005. PMID: 15933268
MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling.
da Costa Martins PA, Salic K, Gladka MM, Armand AS, Leptidis S, el Azzouzi H, Hansen A, Coenen-de Roo CJ, Bierhuizen MF, van der Nagel R, van Kuik J, de Weger R, de Bruin A, Condorelli G, Arbones ML, Eschenhagen T, De Windt LJ. da Costa Martins PA, et al. Among authors: de windt lj, de weger r, de bruin a. Nat Cell Biol. 2010 Dec;12(12):1220-7. doi: 10.1038/ncb2126. Epub 2010 Nov 21. Nat Cell Biol. 2010. PMID: 21102440
Peroxisome proliferator-activated receptor (PPAR) gene profiling uncovers insulin-like growth factor-1 as a PPARalpha target gene in cardioprotection.
el Azzouzi H, Leptidis S, Bourajjaj M, Armand AS, van der Nagel R, van Bilsen M, Da Costa Martins PA, De Windt LJ. el Azzouzi H, et al. Among authors: de windt lj. J Biol Chem. 2011 Apr 22;286(16):14598-607. doi: 10.1074/jbc.M111.220525. Epub 2011 Jan 18. J Biol Chem. 2011. PMID: 21245137 Free PMC article.
NF-kappaB activation is required for adaptive cardiac hypertrophy.
Zelarayan L, Renger A, Noack C, Zafiriou MP, Gehrke C, van der Nagel R, Dietz R, de Windt L, Bergmann MW. Zelarayan L, et al. Cardiovasc Res. 2009 Dec 1;84(3):416-24. doi: 10.1093/cvr/cvp237. Epub 2009 Jul 20. Cardiovasc Res. 2009. PMID: 19620128
EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant.
van Empel VP, Bertrand AT, van Oort RJ, van der Nagel R, Engelen M, van Rijen HV, Doevendans PA, Crijns HJ, Ackerman SL, Sluiter W, De Windt LJ. van Empel VP, et al. Among authors: de windt lj. J Am Coll Cardiol. 2006 Aug 15;48(4):824-32. doi: 10.1016/j.jacc.2006.02.075. Epub 2006 Jul 25. J Am Coll Cardiol. 2006. PMID: 16904556 Free article.
156 results