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A designed zinc-finger transcriptional repressor of phospholamban improves function of the failing heart.
Zhang HS, Liu D, Huang Y, Schmidt S, Hickey R, Guschin D, Su H, Jovin IS, Kunis M, Hinkley S, Liang Y, Hinh L, Spratt SK, Case CC, Rebar EJ, Ehrlich BE, Ehrlich B, Gregory PD, Giordano FJ. Zhang HS, et al. Among authors: liang y. Mol Ther. 2012 Aug;20(8):1508-15. doi: 10.1038/mt.2012.80. Epub 2012 Jul 24. Mol Ther. 2012. PMID: 22828502 Free PMC article.
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.
Liu PQ, Rebar EJ, Zhang L, Liu Q, Jamieson AC, Liang Y, Qi H, Li PX, Chen B, Mendel MC, Zhong X, Lee YL, Eisenberg SP, Spratt SK, Case CC, Wolffe AP. Liu PQ, et al. Among authors: liang y. J Biol Chem. 2001 Apr 6;276(14):11323-34. doi: 10.1074/jbc.M011172200. Epub 2001 Jan 5. J Biol Chem. 2001. PMID: 11145970 Free article.
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