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Page 1
Egis-11150: a candidate antipsychotic compound with procognitive efficacy in rodents.
Gacsályi I, Nagy K, Pallagi K, Lévay G, Hársing LG Jr, Móricz K, Kertész S, Varga P, Haller J, Gigler G, Szénási G, Barkóczy J, Bíró J, Spedding M, Antoni FA. Gacsályi I, et al. Among authors: spedding m. Neuropharmacology. 2013 Jan;64:254-63. doi: 10.1016/j.neuropharm.2012.07.017. Epub 2012 Jul 21. Neuropharmacology. 2013. PMID: 22824189
Behavioural pharmacology of the α5-GABAA receptor antagonist S44819: Enhancement and remediation of cognitive performance in preclinical models.
Gacsályi I, Móricz K, Gigler G, Wellmann J, Nagy K, Ling I, Barkóczy J, Haller J, Lambert JJ, Szénási G, Spedding M, Antoni FA. Gacsályi I, et al. Among authors: spedding m. Neuropharmacology. 2017 Oct;125:30-38. doi: 10.1016/j.neuropharm.2017.07.005. Epub 2017 Jul 8. Neuropharmacology. 2017. PMID: 28694097
Selective inhibition of extra-synaptic α5-GABAA receptors by S44819, a new therapeutic agent.
Etherington LA, Mihalik B, Pálvölgyi A, Ling I, Pallagi K, Kertész S, Varga P, Gunn BG, Brown AR, Livesey MR, Monteiro O, Belelli D, Barkóczy J, Spedding M, Gacsályi I, Antoni FA, Lambert JJ. Etherington LA, et al. Among authors: spedding m. Neuropharmacology. 2017 Oct;125:353-364. doi: 10.1016/j.neuropharm.2017.08.012. Epub 2017 Aug 12. Neuropharmacology. 2017. PMID: 28807671
Effects of EGIS-7625, a selective and competitive 5-HT2B receptor antagonist.
Kovács A, Gacsályi I, Wellmann J, Schmidt E, Szücs Z, Dubreuil V, Nicolas JP, Boutin J, Bózsing D, Egyed A, Tihanyi K, Spedding M, Szénási G. Kovács A, et al. Among authors: spedding m. Cardiovasc Drugs Ther. 2003 Sep-Nov;17(5-6):427-34. doi: 10.1023/b:card.0000015857.96371.43. Cardiovasc Drugs Ther. 2003. PMID: 15107597
(Phenylpiperazinyl-butyl)oxindoles as selective 5-HT7 receptor antagonists.
Volk B, Barkóczy J, Hegedus E, Udvari S, Gacsályi I, Mezei T, Pallagi K, Kompagne H, Lévay G, Egyed A, Hársing LG Jr, Spedding M, Simig G. Volk B, et al. Among authors: spedding m. J Med Chem. 2008 Apr 24;51(8):2522-32. doi: 10.1021/jm070279v. Epub 2008 Mar 25. J Med Chem. 2008. PMID: 18361484
A novel GABA(A) alpha 5 receptor inhibitor with therapeutic potential.
Ling I, Mihalik B, Etherington LA, Kapus G, Pálvölgyi A, Gigler G, Kertész S, Gaál A, Pallagi K, Kiricsi P, Szabó É, Szénási G, Papp L, Hársing LG, Lévay G, Spedding M, Lambert JJ, Belelli D, Barkóczy J, Volk B, Simig G, Gacsályi I, Antoni FA. Ling I, et al. Among authors: spedding m. Eur J Pharmacol. 2015 Oct 5;764:497-507. doi: 10.1016/j.ejphar.2015.07.005. Epub 2015 Jul 11. Eur J Pharmacol. 2015. PMID: 26169564
Phenotypical Screening on Neuronal Plasticity in Hippocampal-Prefrontal Cortex Connectivity Reveals an Antipsychotic with a Novel Profile.
Spedding M, Sebban C, Jay TM, Rocher C, Tesolin-Decros B, Chazot P, Schenker E, Szénási G, Lévay GI, Megyeri K, Barkóczy J, Hársing LG Jr, Thomson I, Cunningham MO, Whittington MA, Etherington LA, Lambert JJ, Antoni FA, Gacsályi I. Spedding M, et al. Cells. 2022 Mar 31;11(7):1181. doi: 10.3390/cells11071181. Cells. 2022. PMID: 35406745 Free PMC article.
The glycine transporter-1 inhibitors NFPS and Org 24461: a pharmacological study.
Harsing LG Jr, Gacsalyi I, Szabo G, Schmidt E, Sziray N, Sebban C, Tesolin-Decros B, Matyus P, Egyed A, Spedding M, Levay G. Harsing LG Jr, et al. Among authors: spedding m. Pharmacol Biochem Behav. 2003 Mar;74(4):811-25. doi: 10.1016/s0091-3057(02)01078-x. Pharmacol Biochem Behav. 2003. PMID: 12667895
2,3-benzodiazepine-type AMPA receptor antagonists and their neuroprotective effects.
Szénási G, Vegh M, Szabo G, Kertesz S, Kapus G, Albert M, Greff Z, Ling I, Barkoczy J, Simig G, Spedding M, Harsing LG Jr. Szénási G, et al. Among authors: spedding m. Neurochem Int. 2008 Jan;52(1-2):166-83. doi: 10.1016/j.neuint.2007.07.002. Epub 2007 Jul 10. Neurochem Int. 2008. PMID: 17707550 Review.
248 results