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Egis-11150: a candidate antipsychotic compound with procognitive efficacy in rodents.
Gacsályi I, Nagy K, Pallagi K, Lévay G, Hársing LG Jr, Móricz K, Kertész S, Varga P, Haller J, Gigler G, Szénási G, Barkóczy J, Bíró J, Spedding M, Antoni FA. Gacsályi I, et al. Among authors: gigler g. Neuropharmacology. 2013 Jan;64:254-63. doi: 10.1016/j.neuropharm.2012.07.017. Epub 2012 Jul 21. Neuropharmacology. 2013. PMID: 22824189
Behavioural pharmacology of the α5-GABAA receptor antagonist S44819: Enhancement and remediation of cognitive performance in preclinical models.
Gacsályi I, Móricz K, Gigler G, Wellmann J, Nagy K, Ling I, Barkóczy J, Haller J, Lambert JJ, Szénási G, Spedding M, Antoni FA. Gacsályi I, et al. Among authors: gigler g. Neuropharmacology. 2017 Oct;125:30-38. doi: 10.1016/j.neuropharm.2017.07.005. Epub 2017 Jul 8. Neuropharmacology. 2017. PMID: 28694097
Loop F of the GABAA receptor alpha subunit governs GABA potency.
Pálvölgyi A, Móricz K, Pataki Á, Mihalik B, Gigler G, Megyeri K, Udvari S, Gacsályi I, Antoni FA. Pálvölgyi A, et al. Among authors: gigler g. Neuropharmacology. 2018 Jan;128:408-415. doi: 10.1016/j.neuropharm.2017.10.042. Epub 2017 Nov 3. Neuropharmacology. 2018. PMID: 29109059
A novel GABA(A) alpha 5 receptor inhibitor with therapeutic potential.
Ling I, Mihalik B, Etherington LA, Kapus G, Pálvölgyi A, Gigler G, Kertész S, Gaál A, Pallagi K, Kiricsi P, Szabó É, Szénási G, Papp L, Hársing LG, Lévay G, Spedding M, Lambert JJ, Belelli D, Barkóczy J, Volk B, Simig G, Gacsályi I, Antoni FA. Ling I, et al. Among authors: gigler g. Eur J Pharmacol. 2015 Oct 5;764:497-507. doi: 10.1016/j.ejphar.2015.07.005. Epub 2015 Jul 11. Eur J Pharmacol. 2015. PMID: 26169564
Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models.
Gigler G, Móricz K, Agoston M, Simó A, Albert M, Benedek A, Kapus G, Kertész S, Vegh M, Barkóczy J, Markó B, Szabó G, Matucz E, Gacsályi I, Lévay G, Hársing LG Jr, Szénási G. Gigler G, et al. Br J Pharmacol. 2007 Sep;152(1):151-60. doi: 10.1038/sj.bjp.0707362. Epub 2007 Jul 2. Br J Pharmacol. 2007. PMID: 17603549 Free PMC article.
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