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Hedgehog signaling regulates bladder cancer growth and tumorigenicity.
Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, Bejarano P, Capobianco AJ, Robbins DJ. Fei DL, et al. Cancer Res. 2012 Sep 1;72(17):4449-58. doi: 10.1158/0008-5472.CAN-11-4123. Epub 2012 Jul 19. Cancer Res. 2012. PMID: 22815529 Free PMC article.
Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma.
Wang Z, Da Silva TG, Jin K, Han X, Ranganathan P, Zhu X, Sanchez-Mejias A, Bai F, Li B, Fei DL, Weaver K, Carpio RV, Moscowitz AE, Koshenkov VP, Sanchez L, Sparling L, Pei XH, Franceschi D, Ribeiro A, Robbins DJ, Livingstone AS, Capobianco AJ. Wang Z, et al. Cancer Res. 2014 Nov 1;74(21):6364-74. doi: 10.1158/0008-5472.CAN-14-2051. Epub 2014 Aug 27. Cancer Res. 2014. PMID: 25164006 Free PMC article.
Noncanonical activation of GLI signaling in SOX2+ cells drives medulloblastoma relapse.
Swiderska-Syn M, Mir-Pedrol J, Oles A, Schleuger O, Salvador AD, Greiner SM, Seward C, Yang F, Babcock BR, Shen C, Wynn DT, Sanchez-Mejias A, Gershon TR, Martin V, McCrea HJ, Lindsey KG, Krieg C, Rodriguez-Blanco J. Swiderska-Syn M, et al. Among authors: sanchez mejias a. Sci Adv. 2022 Jul 22;8(29):eabj9138. doi: 10.1126/sciadv.abj9138. Epub 2022 Jul 20. Sci Adv. 2022. PMID: 35857834 Free PMC article.
Find and cut-and-transfer (FiCAT) mammalian genome engineering.
Pallarès-Masmitjà M, Ivančić D, Mir-Pedrol J, Jaraba-Wallace J, Tagliani T, Oliva B, Rahmeh A, Sánchez-Mejías A, Güell M. Pallarès-Masmitjà M, et al. Among authors: sanchez mejias a. Nat Commun. 2021 Dec 3;12(1):7071. doi: 10.1038/s41467-021-27183-x. Nat Commun. 2021. PMID: 34862378 Free PMC article.
MiR-138 is a potent regulator of the heterogenous MYC transcript population in cancers.
Desi N, Teh V, Tong QY, Lim CY, Tabatabaeian H, Chew XH, Sanchez-Mejias A, Chan JJ, Zhang B, Pitcheshwar P, Siew BE, Wang S, Lee KC, Chong CS, Cheong WK, Lieske B, Tan IJ, Tan KK, Tay Y. Desi N, et al. Among authors: sanchez mejias a. Oncogene. 2022 Feb;41(8):1178-1189. doi: 10.1038/s41388-021-02084-x. Epub 2021 Dec 22. Oncogene. 2022. PMID: 34937878 Free PMC article.
Pan-cancer pervasive upregulation of 3' UTR splicing drives tumourigenesis.
Chan JJ, Zhang B, Chew XH, Salhi A, Kwok ZH, Lim CY, Desi N, Subramaniam N, Siemens A, Kinanti T, Ong S, Sanchez-Mejias A, Ly PT, An O, Sundar R, Fan X, Wang S, Siew BE, Lee KC, Chong CS, Lieske B, Cheong WK, Goh Y, Fam WN, Ooi MG, Koh BTH, Iyer SG, Ling WH, Chen J, Yoong BK, Chanwat R, Bonney GK, Goh BKP, Zhai W, Fullwood MJ, Wang W, Tan KK, Chng WJ, Dan YY, Pitt JJ, Roca X, Guccione E, Vardy LA, Chen L, Gao X, Chow PKH, Yang H, Tay Y. Chan JJ, et al. Among authors: sanchez mejias a. Nat Cell Biol. 2022 Jun;24(6):928-939. doi: 10.1038/s41556-022-00913-z. Epub 2022 May 26. Nat Cell Biol. 2022. PMID: 35618746 Free PMC article.
24 results