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The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes.
He YQ, Sutcliffe EL, Bunting KL, Li J, Goodall KJ, Poon IK, Hulett MD, Freeman C, Zafar A, McInnes RL, Taya T, Parish CR, Rao S. He YQ, et al. Among authors: poon ik. Transcription. 2012 May-Jun;3(3):130-45. doi: 10.4161/trns.19998. Transcription. 2012. PMID: 22771948 Free PMC article.
Novel Formulation of Undecylenic Acid induces Tumor Cell Apoptosis.
Day ZI, Mayfosh AJ, Giel MC, Hong Y, Williams SA, Santavanond JP, Rau TF, Poon IK, Hulett MD. Day ZI, et al. Among authors: poon ik. Int J Mol Sci. 2022 Nov 16;23(22):14170. doi: 10.3390/ijms232214170. Int J Mol Sci. 2022. PMID: 36430646 Free PMC article.
The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity.
Santavanond JP, Chiu YH, Tixeira R, Liu Z, Yap JKY, Chen KW, Li CL, Lu YR, Roncero-Carol J, Hoijman E, Rutter SF, Shi B, Ryan GF, Hodge AL, Caruso S, Baxter AA, Ozkocak DC, Johnson C, Day ZI, Mayfosh AJ, Hulett MD, Phan TK, Atkin-Smith GK, Poon IKH. Santavanond JP, et al. Among authors: poon ikh. Cell Death Dis. 2024 Feb 9;15(2):123. doi: 10.1038/s41419-024-06513-z. Cell Death Dis. 2024. PMID: 38336804 Free PMC article.
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.
Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ; MISEV Consortium; Théry C, Witwer KW. Welsh JA, et al. J Extracell Vesicles. 2024 Feb;13(2):e12404. doi: 10.1002/jev2.12404. J Extracell Vesicles. 2024. PMID: 38326288 Free PMC article.
Targeting Efferocytosis in Inflammaging.
Poon IKH, Ravichandran KS. Poon IKH, et al. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:339-357. doi: 10.1146/annurev-pharmtox-032723-110507. Epub 2023 Aug 16. Annu Rev Pharmacol Toxicol. 2024. PMID: 37585658 Free article. Review.
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