Stiborova M - Search Results

1

Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and 32P-postlabelling.

Arlt VM, Poirier MC, Sykes SE, John K, Moserova M, Stiborova M, Wolf CR, Henderson CJ, Phillips DH. Arlt VM, et al. Among authors: stiborova m. Toxicol Lett. 2012 Sep 3;213(2):160-6. doi: 10.1016/j.toxlet.2012.06.016. Epub 2012 Jul 1. Toxicol Lett. 2012. PMID: 22759596 Free PMC article.

2

Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.

Arlt VM, Stiborova M, Hewer A, Schmeiser HH, Phillips DH. Arlt VM, et al. Among authors: stiborova m. Cancer Res. 2003 Jun 1;63(11):2752-61. Cancer Res. 2003. PMID: 12782579

3

3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.

Arlt VM, Hewer A, Sorg BL, Schmeiser HH, Phillips DH, Stiborova M. Arlt VM, et al. Among authors: stiborova m. Chem Res Toxicol. 2004 Aug;17(8):1092-101. doi: 10.1021/tx049912v. Chem Res Toxicol. 2004. PMID: 15310241

4

Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases.

Arlt VM, Henderson CJ, Wolf CR, Schmeiser HH, Phillips DH, Stiborova M. Arlt VM, et al. Among authors: stiborova m. Cancer Lett. 2006 Mar 28;234(2):220-31. doi: 10.1016/j.canlet.2005.03.035. Cancer Lett. 2006. PMID: 15885895

5

Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: studies with the hepatic NADPH:cytochrome P450 reductase null mouse.

Stiborová M, Arlt VM, Henderson CJ, Wolf CR, Kotrbová V, Moserová M, Hudecek J, Phillips DH, Frei E. Stiborová M, et al. Toxicol Appl Pharmacol. 2008 Feb 1;226(3):318-27. doi: 10.1016/j.taap.2007.09.017. Epub 2007 Sep 26. Toxicol Appl Pharmacol. 2008. PMID: 17976674

6

Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.

Levová K, Moserová M, Kotrbová V, Sulc M, Henderson CJ, Wolf CR, Phillips DH, Frei E, Schmeiser HH, Mares J, Arlt VM, Stiborová M. Levová K, et al. Among authors: stiborova m. Toxicol Sci. 2011 May;121(1):43-56. doi: 10.1093/toxsci/kfr050. Epub 2011 Feb 28. Toxicol Sci. 2011. PMID: 21362632 Free article.

7

Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice.

Arlt VM, Levová K, Bárta F, Shi Z, Evans JD, Frei E, Schmeiser HH, Nebert DW, Phillips DH, Stiborová M. Arlt VM, et al. Among authors: stiborova m. Chem Res Toxicol. 2011 Oct 17;24(10):1710-9. doi: 10.1021/tx200259y. Epub 2011 Sep 29. Chem Res Toxicol. 2011. PMID: 21932800

8

Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adduct formation in P450 reductase conditional null mice.

Arlt VM, Singh R, Stiborová M, Gamboa da Costa G, Frei E, Evans JD, Farmer PB, Wolf CR, Henderson CJ, Phillips DH. Arlt VM, et al. Among authors: stiborova m. Drug Metab Dispos. 2011 Dec;39(12):2169-73. doi: 10.1124/dmd.111.041343. Epub 2011 Sep 22. Drug Metab Dispos. 2011. PMID: 21940903

9

The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice.

Stiborova M, Cerna V, Moserova M, Arlt VM, Frei E. Stiborova M, et al. Neuro Endocrinol Lett. 2013;34 Suppl 2:43-54. Neuro Endocrinol Lett. 2013. PMID: 24362092

10

Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions.

Stiborová M, Moserová M, Černá V, Indra R, Dračínský M, Šulc M, Henderson CJ, Wolf CR, Schmeiser HH, Phillips DH, Frei E, Arlt VM. Stiborová M, et al. Toxicology. 2014 Apr 6;318:1-12. doi: 10.1016/j.tox.2014.02.002. Epub 2014 Feb 14. Toxicology. 2014. PMID: 24530354

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