Baqi Y - Search Results

1

Allosteric modulators of rhodopsin-like G protein-coupled receptors: opportunities in drug development.

Müller CE, Schiedel AC, Baqi Y. Müller CE, et al. Among authors: baqi y. Pharmacol Ther. 2012 Sep;135(3):292-315. doi: 10.1016/j.pharmthera.2012.06.002. Epub 2012 Jun 19. Pharmacol Ther. 2012. PMID: 22728155 Review.

2

Ligand binding and activation of UTP-activated G protein-coupled P2Y₂ and P2Y₄ receptors elucidated by mutagenesis, pharmacological and computational studies.

Attah IY, Neumann A, Al-Hroub H, Rafehi M, Baqi Y, Namasivayam V, Müller CE. Attah IY, et al. Among authors: baqi y. Biochim Biophys Acta Gen Subj. 2020 Mar;1864(3):129501. doi: 10.1016/j.bbagen.2019.129501. Epub 2019 Dec 5. Biochim Biophys Acta Gen Subj. 2020. PMID: 31812541

3

Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor.

Hoffmann K, Baqi Y, Morena MS, Glänzel M, Müller CE, von Kügelgen I. Hoffmann K, et al. Among authors: baqi y. J Pharmacol Exp Ther. 2009 Nov;331(2):648-55. doi: 10.1124/jpet.109.156687. Epub 2009 Aug 18. J Pharmacol Exp Ther. 2009. PMID: 19690189

4

Synthesis of alkyl- and aryl-amino-substituted anthraquinone derivatives by microwave-assisted copper(0)-catalyzed Ullmann coupling reactions.

Baqi Y, Müller CE. Baqi Y, et al. Nat Protoc. 2010 May;5(5):945-53. doi: 10.1038/nprot.2010.63. Epub 2010 Apr 29. Nat Protoc. 2010. PMID: 20431540

5

Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor.

Baqi Y, Hausmann R, Rosefort C, Rettinger J, Schmalzing G, Müller CE. Baqi Y, et al. J Med Chem. 2011 Feb 10;54(3):817-30. doi: 10.1021/jm1012193. Epub 2011 Jan 5. J Med Chem. 2011. PMID: 21207957

6

Convergent synthesis of the potent P2Y receptor antagonist MG 50-3-1 based on a regioselective Ullmann coupling reaction.

Baqi Y, Müller CE. Baqi Y, et al. Molecules. 2012 Mar 5;17(3):2599-615. doi: 10.3390/molecules17032599. Molecules. 2012. PMID: 22391596 Free PMC article.

7

Discovery and Structure Relationships of Salicylanilide Derivatives as Potent, Non-acidic P2X1 Receptor Antagonists.

Tian M, Abdelrahman A, Baqi Y, Fuentes E, Azazna D, Spanier C, Densborn S, Hinz S, Schmid R, Müller CE. Tian M, et al. Among authors: baqi y. J Med Chem. 2020 Jun 11;63(11):6164-6178. doi: 10.1021/acs.jmedchem.0c00435. Epub 2020 May 27. J Med Chem. 2020. PMID: 32345019

8

Molecular Recognition of Agonists and Antagonists by the Nucleotide-Activated G Protein-Coupled P2Y₂ Receptor.

Rafehi M, Neumann A, Baqi Y, Malik EM, Wiese M, Namasivayam V, Müller CE. Rafehi M, et al. Among authors: baqi y. J Med Chem. 2017 Oct 26;60(20):8425-8440. doi: 10.1021/acs.jmedchem.7b00854. Epub 2017 Oct 10. J Med Chem. 2017. PMID: 28938069

9

3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17.

Baqi Y, Pillaiyar T, Abdelrahman A, Kaufmann O, Alshaibani S, Rafehi M, Ghasimi S, Akkari R, Ritter K, Simon K, Spinrath A, Kostenis E, Zhao Q, Köse M, Namasivayam V, Müller CE. Baqi Y, et al. J Med Chem. 2018 Sep 27;61(18):8136-8154. doi: 10.1021/acs.jmedchem.7b01768. Epub 2018 Sep 5. J Med Chem. 2018. PMID: 30048589

10

Antithrombotic P2Y₁₂ receptor antagonists: recent developments in drug discovery.

Baqi Y, Müller CE. Baqi Y, et al. Drug Discov Today. 2019 Jan;24(1):325-333. doi: 10.1016/j.drudis.2018.09.021. Epub 2018 Oct 3. Drug Discov Today. 2019. PMID: 30291899 Review.

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