Wancewicz EV - Search Results

1

Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.

Kordasiewicz HB, Stanek LM, Wancewicz EV, Mazur C, McAlonis MM, Pytel KA, Artates JW, Weiss A, Cheng SH, Shihabuddin LS, Hung G, Bennett CF, Cleveland DW. Kordasiewicz HB, et al. Among authors: wancewicz ev. Neuron. 2012 Jun 21;74(6):1031-44. doi: 10.1016/j.neuron.2012.05.009. Neuron. 2012. PMID: 22726834 Free PMC article.

2

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.

Polymenidou M, Lagier-Tourenne C, Hutt KR, Huelga SC, Moran J, Liang TY, Ling SC, Sun E, Wancewicz E, Mazur C, Kordasiewicz H, Sedaghat Y, Donohue JP, Shiue L, Bennett CF, Yeo GW, Cleveland DW. Polymenidou M, et al. Nat Neurosci. 2011 Apr;14(4):459-68. doi: 10.1038/nn.2779. Epub 2011 Feb 27. Nat Neurosci. 2011. PMID: 21358643 Free PMC article.

3

Antisense oligonucleotide therapy for neurodegenerative disease.

Smith RA, Miller TM, Yamanaka K, Monia BP, Condon TP, Hung G, Lobsiger CS, Ward CM, McAlonis-Downes M, Wei H, Wancewicz EV, Bennett CF, Cleveland DW. Smith RA, et al. Among authors: wancewicz ev. J Clin Invest. 2006 Aug;116(8):2290-6. doi: 10.1172/JCI25424. Epub 2006 Jul 27. J Clin Invest. 2006. PMID: 16878173 Free PMC article.

4

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.

Lagier-Tourenne C, Polymenidou M, Hutt KR, Vu AQ, Baughn M, Huelga SC, Clutario KM, Ling SC, Liang TY, Mazur C, Wancewicz E, Kim AS, Watt A, Freier S, Hicks GG, Donohue JP, Shiue L, Bennett CF, Ravits J, Cleveland DW, Yeo GW. Lagier-Tourenne C, et al. Nat Neurosci. 2012 Nov;15(11):1488-97. doi: 10.1038/nn.3230. Epub 2012 Sep 30. Nat Neurosci. 2012. PMID: 23023293 Free PMC article.

5

Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals.

Swayze EE, Siwkowski AM, Wancewicz EV, Migawa MT, Wyrzykiewicz TK, Hung G, Monia BP, Bennett CF. Swayze EE, et al. Among authors: wancewicz ev. Nucleic Acids Res. 2007;35(2):687-700. doi: 10.1093/nar/gkl1071. Epub 2006 Dec 19. Nucleic Acids Res. 2007. PMID: 17182632 Free PMC article.

6

Time-dependent, bidirectional, anti- and pro-spinal hyper-reflexia and muscle spasticity effect after chronic spinal glycine transporter 2 (GlyT2) oligonucleotide-induced downregulation.

Kamizato K, Marsala S, Navarro M, Kakinohana M, Platoshyn O, Yoshizumi T, Lukacova N, Wancewicz E, Powers B, Mazur C, Marsala M. Kamizato K, et al. Exp Neurol. 2018 Jul;305:66-75. doi: 10.1016/j.expneurol.2018.03.013. Epub 2018 Mar 30. Exp Neurol. 2018. PMID: 29608917

7

Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice.

Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB. Nazor Friberg K, et al. Mol Ther Nucleic Acids. 2012 Feb 7;1(2):e9. doi: 10.1038/mtna.2011.6. Mol Ther Nucleic Acids. 2012. PMID: 23344724 Free PMC article.

8

Development of a simple, rapid, and robust intrathecal catheterization method in the rat.

Mazur C, Fitzsimmons B, Kamme F, Nichols B, Powers B, Wancewicz E. Mazur C, et al. J Neurosci Methods. 2017 Mar 15;280:36-46. doi: 10.1016/j.jneumeth.2017.02.001. Epub 2017 Feb 2. J Neurosci Methods. 2017. PMID: 28163066

9

Inhibition of spinal cytosolic phospholipase A(2) expression by an antisense oligonucleotide attenuates tissue injury-induced hyperalgesia.

Kim DH, Fitzsimmons B, Hefferan MP, Svensson CI, Wancewicz E, Monia BP, Hung G, Butler M, Marsala M, Hua XY, Yaksh TL. Kim DH, et al. Neuroscience. 2008 Jun 26;154(3):1077-87. doi: 10.1016/j.neuroscience.2008.04.033. Epub 2008 Apr 30. Neuroscience. 2008. PMID: 18511207 Free PMC article.

10

Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue.

Wancewicz EV, Maier MA, Siwkowski AM, Albertshofer K, Winger TM, Berdeja A, Gaus H, Vickers TA, Bennett CF, Monia BP, Griffey RH, Nulf CJ, Hu J, Corey DR, Swayze EE, Kinberger GA. Wancewicz EV, et al. J Med Chem. 2010 May 27;53(10):3919-26. doi: 10.1021/jm901489k. J Med Chem. 2010. PMID: 20420385 Free PMC article.

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