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A2A adenosine receptor antagonism enhances synaptic and motor effects of cocaine via CB1 cannabinoid receptor activation.
Tozzi A, de Iure A, Marsili V, Romano R, Tantucci M, Di Filippo M, Costa C, Napolitano F, Mercuri NB, Borsini F, Giampà C, Fusco FR, Picconi B, Usiello A, Calabresi P. Tozzi A, et al. Among authors: borsini f. PLoS One. 2012;7(6):e38312. doi: 10.1371/journal.pone.0038312. Epub 2012 Jun 8. PLoS One. 2012. PMID: 22715379 Free PMC article.
Synthesis and biological evaluation of metabolites of 2-n-butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), a potent antagonist of the A2A adenosine receptor for the treatment of Parkinson's disease.
Piersanti G, Bartoccini F, Lucarini S, Cabri W, Stasi MA, Riccioni T, Borsini F, Tarzia G, Minetti P. Piersanti G, et al. Among authors: borsini f. J Med Chem. 2013 Jul 11;56(13):5456-63. doi: 10.1021/jm400491x. Epub 2013 Jun 24. J Med Chem. 2013. PMID: 23789814
ST 1535: a preferential A2A adenosine receptor antagonist.
Stasi MA, Borsini F, Varani K, Vincenzi F, Di Cesare MA, Minetti P, Ghirardi O, Carminati P. Stasi MA, et al. Among authors: borsini f. Int J Neuropsychopharmacol. 2006 Oct;9(5):575-84. doi: 10.1017/S1461145705006188. Epub 2005 Nov 23. Int J Neuropsychopharmacol. 2006. PMID: 16867213 Free article.
Animal models of Parkinson׳s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535).
Stasi MA, Minetti P, Lombardo K, Riccioni T, Caprioli A, Vertechy M, Di Serio S, Pace S, Borsini F. Stasi MA, et al. Among authors: borsini f. Eur J Pharmacol. 2015 Aug 15;761:353-61. doi: 10.1016/j.ejphar.2015.03.070. Epub 2015 Apr 30. Eur J Pharmacol. 2015. PMID: 25936513
148 results