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A recombinant 63-kDa form of Bacillus anthracis protective antigen produced in the yeast Saccharomyces cerevisiae provides protection in rabbit and primate inhalational challenge models of anthrax infection.
Hepler RW, Kelly R, McNeely TB, Fan H, Losada MC, George HA, Woods A, Cope LD, Bansal A, Cook JC, Zang G, Cohen SL, Wei X, Keller PM, Leffel E, Joyce JG, Pitt L, Schultz LD, Jansen KU, Kurtz M. Hepler RW, et al. Vaccine. 2006 Mar 6;24(10):1501-14. doi: 10.1016/j.vaccine.2005.10.018. Epub 2005 Oct 21. Vaccine. 2006. PMID: 16271808
Short-course postexposure antibiotic prophylaxis combined with vaccination protects against experimental inhalational anthrax.
Vietri NJ, Purcell BK, Lawler JV, Leffel EK, Rico P, Gamble CS, Twenhafel NA, Ivins BE, Heine HS, Sheeler R, Wright ME, Friedlander AM. Vietri NJ, et al. Among authors: leffel ek. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7813-6. doi: 10.1073/pnas.0602748103. Epub 2006 May 3. Proc Natl Acad Sci U S A. 2006. PMID: 16672361 Free PMC article.
Marburg and Ebola viruses as aerosol threats.
Leffel EK, Reed DS. Leffel EK, et al. Biosecur Bioterror. 2004;2(3):186-91. doi: 10.1089/bsp.2004.2.186. Biosecur Bioterror. 2004. PMID: 15588056
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