Fancher RM - Search Results

1

Utility of in situ sodium alginate/karaya gum gels to facilitate gastric retention in rodents.

Foster KA, Morgen M, Murri B, Yates I, Fancher RM, Ehrmann J, Gudmundsson OS, Hageman MJ. Foster KA, et al. Among authors: fancher rm. Int J Pharm. 2012 Sep 15;434(1-2):406-12. doi: 10.1016/j.ijpharm.2012.06.009. Epub 2012 Jun 9. Int J Pharm. 2012. PMID: 22692076

2

Utility of gastric-retained alginate gels to modulate pharmacokinetic profiles in rats.

Foster KA, Sun H, Fancher RM, Proszynski M, Dixon G, Ford K, Cornelius G, Gudmundsson OS, Hageman MJ. Foster KA, et al. Among authors: fancher rm. J Pharm Sci. 2013 Aug;102(8):2440-9. doi: 10.1002/jps.23630. Epub 2013 Jun 6. J Pharm Sci. 2013. PMID: 23744594

3

Development of a canine model to enable the preclinical assessment of pH-dependent absorption of test compounds.

Fancher RM, Zhang H, Sleczka B, Derbin G, Rockar R, Marathe P. Fancher RM, et al. J Pharm Sci. 2011 Jul;100(7):2979-88. doi: 10.1002/jps.22486. Epub 2011 Jan 19. J Pharm Sci. 2011. PMID: 21254068

4

Investigation of the "true" extraction recovery of analytes from multiple types of tissues and its impact on tissue bioanalysis using two model compounds.

Yuan L, Ma L, Dillon L, Fancher RM, Sun H, Zhu M, Lehman-McKeeman L, Aubry AF, Ji QC. Yuan L, et al. Among authors: fancher rm. Anal Chim Acta. 2016 Nov 16;945:57-66. doi: 10.1016/j.aca.2016.09.039. Epub 2016 Oct 5. Anal Chim Acta. 2016. PMID: 27968716

5

A convenient strategy to overcome interference in LC-MS/MS analysis: Application in a microdose absolute bioavailability study.

Yuan L, Huang C, Liu-Kreyche P, Voronin K, Fancher RM, Allentoff A, Zheng N, Iyer R, Zhu L, Pillutla R, Ji QC. Yuan L, et al. Among authors: fancher rm. J Pharm Biomed Anal. 2019 Feb 20;165:198-206. doi: 10.1016/j.jpba.2018.12.014. Epub 2018 Dec 10. J Pharm Biomed Anal. 2019. PMID: 30553110

6

Evaluation of rosuvastatin as an organic anion transporting polypeptide (OATP) probe substrate: in vitro transport and in vivo disposition in cynomolgus monkeys.

Shen H, Su H, Liu T, Yao M, Mintier G, Li L, Fancher RM, Iyer R, Marathe P, Lai Y, Rodrigues AD. Shen H, et al. Among authors: fancher rm. J Pharmacol Exp Ther. 2015 May;353(2):380-91. doi: 10.1124/jpet.114.221804. Epub 2015 Mar 4. J Pharmacol Exp Ther. 2015. PMID: 25740896

7

Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation.

Shen H, Liu T, Jiang H, Titsch C, Taylor K, Kandoussi H, Qiu X, Chen C, Sukrutharaj S, Kuit K, Mintier G, Krishnamurthy P, Fancher RM, Zeng J, Rodrigues AD, Marathe P, Lai Y. Shen H, et al. Among authors: fancher rm. Drug Metab Dispos. 2016 Feb;44(2):238-49. doi: 10.1124/dmd.115.066852. Epub 2015 Nov 25. Drug Metab Dispos. 2016. PMID: 26608080

8

Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition.

Gu X, Wang L, Gan J, Fancher RM, Tian Y, Hong Y, Lai Y, Sinz M, Shen H. Gu X, et al. Among authors: fancher rm. Drug Metab Dispos. 2020 Aug;48(8):724-734. doi: 10.1124/dmd.120.090670. Epub 2020 Jun 1. Drug Metab Dispos. 2020. PMID: 32482623

9

Increasing the Reuse of Protein Non-Naïve Nonhuman Primates in Pharmaceutical Drug Discovery and Development: An Overview and Industry Position on the Challenges and Benefits.

Mattis C, Bratcher N, Burns M, Carosino C, de Zafra C, Fancher RM, Georgi K, Graff C, Hukkanen RR, Johnson C, Lao Y, Lange A, Lee D, Lepherd M, Maguire S, Malisauskas M, Manuel M, Miranda S, Reed L, Santos R, Sayers B, Shaw D, Shuster D. Mattis C, et al. Among authors: fancher rm. Int J Toxicol. 2022 Aug;41(4):291-296. doi: 10.1177/10915818221101791. Epub 2022 Jun 2. Int J Toxicol. 2022. PMID: 35656559

10

Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement.

Li W, Zhao W, Liu X, Huang X, Lopez OD, Leet JE, Fancher RM, Nguyen V, Goodrich J, Easter J, Hong Y, Caceres-Cortes J, Chang SY, Ma L, Belema M, Hamann LG, Gao M, Zhu M, Shu YZ, Humphreys WG, Johnson BM. Li W, et al. Among authors: fancher rm. Drug Metab Dispos. 2016 Jun;44(6):809-20. doi: 10.1124/dmd.115.068866. Epub 2016 Mar 30. Drug Metab Dispos. 2016. PMID: 27029743

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